ZAK Produkte
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
Kategorien
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte ZAK Kategorien
ZAK Antikörper
High quality antibodies with extensive validation data.
ZAK ELISA Kits
Reliable ELISA kits for a wide range of species.
ZAK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ZAK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (3)
- (5)
Kat. Nr.
ABIN565679
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN6150360
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN392643
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ZAK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1142997
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN5595441
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ZAK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
Kat. Nr.
ABIN1325564
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570540
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325566
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ZAK Produkten
: "NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II." in: Cell death & disease, Vol. 7, Issue 8, pp. e2346, (2017) (PubMed).: "A Requirement for ZAK Kinase Activity in Canonical TGF-β Signaling." in: Translational oncology, Vol. 9, Issue 6, pp. 473-481, (2016) (PubMed).
: "Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. ..." in: Nature communications, Vol. 5, pp. 3830, (2014) (PubMed).
: "A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy." in: Molecular and cellular biology, Vol. 33, Issue 15, pp. 2903-17, (2013) (PubMed).
: "A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in ?1-adrenergic receptor-induced p38 activation." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 7925-37, (2011) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
Synonyme und alternative Namen zu ZAK
mitogen-activated protein kinase kinase kinase 20 (Map3k20), mitogen-activated protein kinase kinase kinase 20 (MAP3K20), AV006891, AZK, B230120H23Rik, MLK7, mlklak, MLT, MLTK, MLTKalpha, MLTKbeta, MRK, pk, RGD1561394Bezeichner auf Proteinebene für ZAK
- mitogen-activated protein kinase kinase kinase MLT
- HCCS-4
- MLK-like mitogen-activated protein triple kinase
- human cervical cancer suppressor gene 4 protein
- mixed lineage kinase 7
- mixed lineage kinase with a leucine zipper and a sterile alpha motif
- mixed lineage kinase-related kinase MRK-beta
- MLK-related kinase
- MRK
- leucine zipper- and sterile alpha motif kinase ZAK
- mixed lineage kinase-related kinase
- sterile alpha motif- and leucine zipper-containing kinase AZK
- sterile-alpha motif and leucine zipper containing kinase AZK
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