anti-DAAM1 (DAAM1) Antikörper

Xenopus laevis Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) Interaktionspartner

1. Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells

2. Daams are expressed in tissues known to require Wnts, so effectors of Wnt (zeige WNT2 Antikörper) signaling during vertebrate development.

Human Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) Interaktionspartner

1. DAAM1 organizes actin filaments into a nodal complex

2. Kank1 (zeige ANKRD15 Antikörper) plays a crucial role in regulating the activity of RhoA (zeige RHOA Antikörper) through retrieving excess Daam1 and balancing the activities of RhoA (zeige RHOA Antikörper) and its effectors.

3. High Daam-1 expression may upregulate the Wnt (zeige WNT2 Antikörper)/PCP (zeige PRCP Antikörper) pathway and cause idiopathic pulmonary arterial hypertension

4. Kif26b (zeige KIF26B Antikörper), together with Dvl3 (zeige DVL3 Antikörper)/Daam1, initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells.

5. Daam1 plays a dual role in the phagocytic uptake of borreliae.

6. A developmentally restricted function of miR (zeige MLXIP Antikörper)-490 and its putative DAAM1 target are associated with exaggerated megakaryocytopoiesis and/or proplatelet formation.

7. Wnt5a (zeige WNT5A Antikörper) promotes breast cancer cell migration via Dvl2 (zeige DVL2 Antikörper)/Daam1/RhoA (zeige RHOA Antikörper).

8. DAAM1 is a formin (zeige FMN1 Antikörper) required for centrosome re-orientation during cell migration.

9. Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs.

10. DAAM1 regulates endothelial cell growth through MT stabilization in a cell type-selective manner

Mouse (Murine) Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) Interaktionspartner

1. The data suggested that Daam1 affected actin assembly during oocyte meiotic division via the regulation of fascin (zeige FSCN1 Antikörper) expression.

2. DAAM1 organizes actin filaments into a nodal complex

3. DAAM1 loss evokes invasive abilities of epithelial cells.

4. Daam1 knockout mice that were also homozygous for Daam2 had stronger noncompaction cardiomyopathy, severely reduced cardiac function, disrupted sarcomere structure, and increased myocardial proliferation.

5. Fascin and Daam1 coimmunoprecipitated from cell extracts, and silencing of fascin led to a striking loss of Daam1 localization to filopodial shafts. Purified fascin bound directly to Daam1; fascin recruited Daam1 to and stabilized Daam1 on actin bundles.

6. Daam1 is important for regulating filamentous actin assembly and organization, and consequently for cytoskeletal function in cardiomyocytes, which contributes to proper heart morphogenesis.

7. Daams are expressed in tissues known to require Wnts, so effectors of Wnt (zeige WNT2 Antikörper) signaling during vertebrate development.

8. a carboxyl-terminal binding partner, Dvl (zeige DVL1 Antikörper), has a role in activation of Daam1

Zebrafish Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) Interaktionspartner

1. Results indicate that Daam1a plays a key role in asymmetric habenular morphogenesis mediating the growth of dendritic and axonal processes in dorsal habenular neurons.

2. Pronephric tubulogenesis requires the Daam1/WGEF (zeige ARHGEF19 Antikörper)/Rho PCP (zeige PRCP Antikörper) pathway.

3. Daam1 is a dynamic coordinator of endocytosis and cytoskeletal remodeling underlying the convergent extension movement of notochord cells.