WASF1 Produkte
(WAS Protein Family, Member 1 (WASF1))
Kategorien
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte WASF1 Kategorien
WASF1 Antikörper
High quality antibodies with extensive validation data.
WASF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
WASF1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene WASF1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7175830
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6266012
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7138927
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene WASF1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380279
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene WASF1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325156
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3075433
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren WASF1 Produkten
: "Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion." in: The EMBO journal, Vol. 33, Issue 23, pp. 2745-64, (2014) (PubMed).: "The WAVE regulatory complex links diverse receptors to the actin cytoskeleton." in: Cell, Vol. 156, Issue 1-2, pp. 195-207, (2014) (PubMed).
: "Local F-actin network links synapse formation and axon branching." in: Cell, Vol. 156, Issue 1-2, pp. 208-20, (2014) (PubMed).
: "SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties." in: Nature, Vol. 503, Issue 7474, pp. 72-7, (2013) (PubMed).
: "Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na+ channel." in: Hypertension (Dallas, Tex. : 1979), Vol. 57, Issue 5, pp. 996-1002, (2011) (PubMed).
: "Rac1 regulates neuronal polarization through the WAVE complex." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 20, pp. 6930-43, (2010) (PubMed).
: "Major signaling pathways in migrating neuroblasts." in: Frontiers in molecular neuroscience, Vol. 2, pp. 7, (2009) (PubMed).
: "WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2." in: Nature cell biology, Vol. 10, Issue 7, pp. 849-57, (2008) (PubMed).
: "Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 7, pp. 1519-28, (2007) (PubMed).
: "Src-dependent phosphorylation of Scar1 promotes its association with the Arp2/3 complex." in: Cell motility and the cytoskeleton, Vol. 63, Issue 1, pp. 6-13, (2006) (PubMed).
Synonyme und alternative Namen zu WASF1
WAS protein family member 1 S homeolog (wasf1.S), SCAR family protein (AT2G34150), WAS protein family member 1 (wasf1), WAS protein family member 1 (WASF1), WAS protein family, member 1 (Wasf1), AI195380, AI838537, ATRANGAP2, ATSCAR1, Scar, scar1, SCAR1, T14G11.27, T14G11_27, wave, WAVE, WAVE-1, wave1, WAVE1, WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1Bezeichner auf Proteinebene für WASF1
- WASP family protein member 1
- homology of dictyostelium scar 1
- protein WAVE-1
- verprolin homology domain-containing protein 1
- wiskott-Aldrich syndrome protein family member 1
- WASP family 1
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