(Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012].
custom-made
UHRF2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
UHRF2
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
ubiquitin like with PHD and ring finger domains 2 (UHRF2) Proteine ubiquitin-like, containing PHD and RING finger domains 2 (Uhrf2) Proteine ubiquitin like with PHD and ring finger domains 2 (Uhrf2) Proteine ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog (uhrf2.L) Proteine 2310065A22Rik Proteine AI426270 Proteine AW214556 Proteine D130071B19Rik Proteine NIRF Proteine Nirf Proteine RNF107 Proteine URF2 Proteine