UGT1A8 Protein (Myc-DYKDDDDK Tag)
Dieses Recombinant UGT1A8-Protein wird in HEK-293 Cells exprimiert.
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Produktnummer ABIN2734969
Kurzübersicht für UGT1A8 Protein (Myc-DYKDDDDK Tag) (ABIN2734969)
Target
UGT1A8
(UDP Glucuronosyltransferase 1 Family, Polypeptide A8 (UGT1A8))
Protein-Typ
Recombinant
Spezies
Human
Quelle
HEK-293 Cells
Applikation
Antibody Production (AbP), Standard (STD)
Reinheit
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Aufreinigungstag / Konjugat
- Dieses UGT1A8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
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Produktmerkmale
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- Recombinant human UDP glucuronosyltransferase 1 family, polypeptide A8 (UGT1A8) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- UGT1A8 (UDP Glucuronosyltransferase 1 Family, Polypeptide A8 (UGT1A8))
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Hintergrund
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5&apos exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity with many substrates including coumarins, phenols, anthraquinones, flavones, and some opioids.
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Molekulargewicht
- 57.1 kDa
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NCBI Accession
- NP_061949
Target
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