UCP2 Produkte
(Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
Kategorien
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008].
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Ausgewählte UCP2 Kategorien
UCP2 Antikörper
High quality antibodies with extensive validation data.
UCP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
UCP2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene UCP2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF
Validierungen
- (7)
Kat. Nr.
ABIN5539644
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7428086
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7435031
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene UCP2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6971067
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960374
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6960376
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene UCP2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324536
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3098710
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396562
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UCP2 Produkten
: "Dose-dependent reproductive toxicity of sodium benzoate in male rats: Inflammation, oxidative stress and apoptosis." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 98, pp. 92-98, (2020) (PubMed).: "Significant Association Between Low Mitochondrial DNA Content in Peripheral Blood Leukocytes and Ischemic Stroke." in: Journal of the American Heart Association, Vol. 6, Issue 11, (2018) (PubMed).
: "Vitamin C and E chronic supplementation differentially affect hepatic insulin signaling in rats." in: Life sciences, Vol. 194, pp. 196-204, (2018) (PubMed).
: "The effect of delivery type on uncoupling protein-2 levels." in: The journal of maternal-fetal & neonatal medicine, Vol. 29, Issue 18, pp. 2940-3, (2016) (PubMed).
: "Methylglyoxal Impairs Insulin Secretion of Pancreatic β-Cells through Increased Production of ROS and Mitochondrial Dysfunction Mediated by Upregulation of UCP2 and MAPKs." in: Journal of diabetes research, Vol. 2016, pp. 2029854, (2016) (PubMed).
: "Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner." in: Biochimica et biophysica acta, Vol. 1853, Issue 3, pp. 549-60, (2015) (PubMed).
: "The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses." in: Journal of neurochemistry, Vol. 135, Issue 1, pp. 147-56, (2015) (PubMed).
: "Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction." in: Cell, Vol. 157, Issue 4, pp. 882-96, (2014) (PubMed).
: "S-adenosyl methionine prevents endothelial dysfunction by inducing heme oxygenase-1 in vascular endothelial cells." in: Molecules and cells, Vol. 36, Issue 4, pp. 376-84, (2014) (PubMed).
: "Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 1, pp. 133-41, (2014) (PubMed).
Synonyme und alternative Namen zu UCP2
mitochondrial uncoupling protein 2 (PTRG_09289), uncoupling protein 2 (UCP2), mitochondrial uncoupling protein 2 (LOC100282746), uncoupling protein 2 (mitochondrial, proton carrier) L homeolog (ucp2.L), uncoupling protein 2 (mitochondrial, proton carrier) (ucp2), uncoupling protein 2 (ucp2), uncoupling protein 1 (ucp1), uncoupling protein 2 (mitochondrial, proton carrier) (Ucp2), uncoupling protein 2 (Ucp2), ATUCP2, BMIQ4, cb74, DKFZp470P1633, K19M22.21, K19M22_21, MGC53319, MGC75881, SLC25A8, Slc25a8, UCP2, ucp2, UCPH, uncoupling protein 2Bezeichner auf Proteinebene für UCP2
- mitochondrial uncoupling protein 2
- uncoupling protein 2 (mitochondrial, proton carrier)
- Mitochondrial uncoupling protein 2
- uncoupling protein 2
- UCP 2
- solute carrier family 25 member 8
- zUCP2
- UCPH
- uncoupling protein 2, mitochondrial
- uncoupling protein homolog
- Uncoupling protein 2, mitochondrial
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