UBE2D1 Produkte
(Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
Kategorien
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Ausgewählte UBE2D1 Kategorien
UBE2D1 Antikörper
High quality antibodies with extensive validation data.
UBE2D1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene UBE2D1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN521211
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7259985
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7174434
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene UBE2D1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951479
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6222221
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene UBE2D1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7544963
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125608
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324340
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UBE2D1 Produkten
: "UBE2L3 polymorphism amplifies NF-?B activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases." in: American journal of human genetics, Vol. 96, Issue 2, pp. 221-34, (2015) (PubMed).: "The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase." in: Journal of virology, Vol. 88, Issue 10, pp. 5437-43, (2014) (PubMed).
: "Exposure to cigarette smoke induces overexpression of von Hippel-Lindau tumor suppressor in mouse skeletal muscle." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 303, Issue 6, pp. L519-27, (2012) (PubMed).
: "A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter." in: Nature cell biology, Vol. 5, Issue 8, pp. 754-61, (2003) (PubMed).
: "UbcH5A, a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, a stimulator of iron transport, and is up-regulated in hereditary hemochromatosis." in: Blood, Vol. 101, Issue 8, pp. 3288-93, (2003) (PubMed).
: "Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 19, pp. 10430-5, (2000) (PubMed).
Synonyme und alternative Namen zu UBE2D1
ubiquitin conjugating enzyme E2 D1 (UBE2D1), ubiquitin-conjugating enzyme E2D 1 (Ube2d1), ubiquitin-conjugating enzyme E2D 1b (ube2d1b), ubiquitin conjugating enzyme E2 D1 S homeolog (ube2d1.S), ubiquitin conjugating enzyme E2 D1 (ube2d1), ubiquitin conjugating enzyme E2 D1 (Ube2d1), E2(17)KB1, e2(17)kb1, SFT, sft, UBC4/5, ubc4/5, UBCH5, ubch5, UBCH5A, ubch5a, ube2d1, wu:fc16h06, zgc:73096Bezeichner auf Proteinebene für UBE2D1
- UBC4/5 homolog
- stimulator of Fe transport
- ubiquitin carrier protein D1
- ubiquitin-conjugating enzyme E2 D1
- ubiquitin-conjugating enzyme E2(17)KB 1
- ubiquitin-conjugating enzyme E2-17 kDa 1
- ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
- ubiquitin-protein ligase D1
- E2(17)KB 1
- ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog
- ubiquitin-conjugating enzyme E2D 1
- ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog)
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