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Human Polyclonal ZEB2 Primary Antibody für IHC, IHC (p) - ABIN4366808
Cai, Luo, Chen, Pei, Lu, Hou, Yun: Overexpression of ZEB2 in peritumoral liver tissue correlates with favorable survival after curative resection of hepatocellular carcinoma. in PLoS ONE 2012
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Cow (Bovine) Polyclonal ZEB2 Primary Antibody für IHC, WB - ABIN2780948
Verstappen, van Grunsven, Michiels, Van de Putte, Souopgui, Van Damme, Bellefroid, Vandekerckhove, Huylebroeck: Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex. in Human molecular genetics 2008
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Human Polyclonal ZEB2 Primary Antibody für IHC, ELISA - ABIN1533518
Harada, Miyake, Kusuda, Fujisawa: Expression of epithelial-mesenchymal transition markers in renal cell carcinoma: impact on prognostic outcomes in patients undergoing radical nephrectomy. in BJU international 2012
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Human Polyclonal ZEB2 Primary Antibody für IHC (p), WB - ABIN317804
He, Xiao, Zhang, Ma, Li, Yang: Detection and functional annotation of misregulated microRNAs in the brain of the Ts65Dn mouse model of Down syndrome. in Chinese medical journal 2013
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Human Monoclonal ZEB2 Primary Antibody für IF, ELISA - ABIN523264
Pogribny, Muskhelishvili, Tryndyak, Beland: The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation. in Toxicology and applied pharmacology 2009
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Human Polyclonal ZEB2 Primary Antibody für WB - ABIN523261
Kumar, Kotlyarevska, Dejkhmaron, Reddy, Lu, Bhojani, Menon et al.: Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for ... in The Journal of biological chemistry 2010
Human Monoclonal ZEB2 Primary Antibody für IF, WB - ABIN395497
Minn, Lee, Hyung, Kim, Choi, Yang, Song, Lim, Kim: MicroRNA-200 family members and ZEB2 are associated with brain metastasis in gastric adenocarcinoma. in International journal of oncology 2014
Human Polyclonal ZEB2 Primary Antibody für ELISA, ICC - ABIN4366807
Xu, Zhu, Zhao, Chen, Zhang, Yuan, Deng, Dou, Wang, Huang, Chen, Jiang, Yu: Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors. in Oncotarget 2015
The pathogenicity of ZEB2 loss of heterozygosity in bovine is described.
Our study confirms that the two susceptibility loci ZFHX1B and SNTB1 are associated with moderate to high myopia in a Han Chinese population, as well as in a European population, when both SNPs are combined.
High expression of ZEB2 is associated with drug resistance in gastric cancer.
The present study validated the prognostic value and clinicopathological association of ZEB1 (zeige ZEB1 Antikörper) and ZEB2 in digestive cancers, especially in gastric cancer.
ZEB2 suppress apoptosis of vascular endothelial cells induced by high glucose through MAPK (zeige MAPK1 Antikörper) pathway activation, which provides a novel insight and therapeutic target for endothelial injury.
Study found SIP1 (zeige GEMIN2 Antikörper) expression was up-regulated and closely related to diminished survival in intrahepatic cholangiocarcinoma (ICC) patients. It is the direct and functional target of miR (zeige MLXIP Antikörper)-590-3p in ICC cells.
miR (zeige MLXIP Antikörper)-30a-5p directly targeted the 3'-UTR (zeige UTS2R Antikörper) of ZEB2 and suppressed clear cell renal cell epithelial-mesenchymal transition.
Our data demonstrate a directly negative feedback loop between miR (zeige MLXIP Antikörper)-203 and ZEB2 participating in tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma
ZEB2 expression was higher in HCC (zeige FAM126A Antikörper) tissues and was negatively related to miR (zeige MLXIP Antikörper)-211-5p levels.
Study shows that ZEB2 expression is controlled at protein synthesis level in cancer cells. Authors propose that the underlying mechanism represents a novel regulatory scheme based on ribosome pausing and degradation of the nascent peptide.
Simultaneous knockdown of both ZEB1 (zeige ZEB1 Antikörper) and ZEB2 expression establishes ZEB1 (zeige ZEB1 Antikörper) as a transcriptional repressor of E-cadherin (zeige CDH1 Antikörper) and a driver of docetaxel resistance in docetaxel-resistant prostate cancer cells.
Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate
We demonstrate that neocortical neurons that have only one copy of Sip1 (heterozygous, Sip1(fI/wt)), are more sensitive to both NMDA- and AMPA (zeige GRIA3 Antikörper)- receptors agonists as compared to wild type neurons (Sip1(wt/wt)).
Zeb2 is critical in embryonic stem cells for exit from the epiblast state.
characterization of differentiation dynamics reveals that Sip1 has a role in promoting the timely differentiation of retinal interneurons, assuring generation of the proper number of the diverse neuronal and glial cell subtypes that constitute the functional retina in mammals.
Collectively, the results demonstrate that Zeb2 controls adult hematopoietic differentiation and lineage fidelity through widespread modulation of dominant signaling pathways that may contribute to blood disorders.
Zeb2 controls Schwann cell maturation by recruiting HDAC1 (zeige HDAC1 Antikörper)/2-NuRD complexes and inhibiting a Notch (zeige NOTCH1 Antikörper)-Hey2 (zeige HEY2 Antikörper) signaling axis
that Zeb2, although undetectable in adult Schwann cells, has a latent function throughout life
ZEB2 transcriptionally represses genes that regulate myeloid differentiation, including genes involved in cell adhesion and migration; epigenetic silencing of the miR (zeige MLXIP Antikörper)-200 family microRNAs affects ZEB2 expression.
Zeb2 regulates commitment to both the cDC2 and pDC lineages through repression of Id2.
The Ppa (zeige FBXL14 Antikörper) could also target the third core EMT (zeige ITK Antikörper) regulatory factor Sip1 (zeige GEMIN2 Antikörper) for proteasomal degradation.
Data show that zebrafish sip1a and sip1b are essential for normal axial and neural patterning.
Knockdown of ChCh (zeige CHURC1 Antikörper) or Sip1a results in misshapen somites that are short and narrow.
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.
zinc finger homeobox 1b
, zinc finger E-box-binding homeobox 2
, SMAD interacting protein 1
, Smad-interacting protein 1
, smad-interacting protein 1
, zinc finger homeobox protein 1b
, smad interaction protein 1
, zinc finger E-box binding homeobox 2
, zinc finger homeobox protein
, Smad-interacting protein-1a
, transcription factor SIP1a
, Smad-interacting protein-1b
, transcription factor SIP1b