anti-TRIM71 (TRIM71) Antikörper

Bezeichnung:: anti-Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase Antikörper (TRIM71)

Auf www.antikoerper-online.de finden Sie aktuell 64 Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) Antikörper von 0 unterschiedlichen Herstellern. Insgesamt sind aktuell 75 TRIM71 Produkte verfügbar.

Synonyme:: 2610206G21Rik, AL022943, Gm1127, lin-41, Lin41, mlin-41, mLin41, RGD1566388, Ripply2

Alle Antikörper anzeigen	Gen	GeneID	UniProt
Anti-Human TRIM71	TRIM71	131405	Q2Q1W2
Anti-Ratte TRIM71	TRIM71	301042
Anti-Maus TRIM71	TRIM71	636931	Q1PSW8
Weitere Synonyme anzeigen

Verknüpfte Pathways mit anti-TRIM71 Antikörper

Tube Formation

Weitere Produktkategorien zu TRIM71 Antikörper

Am meisten referenzierte anti-TRIM71 Antikörper

Human Polyclonal TRIM71 Primary Antibody für ELISA, WB - ABIN4331053 : Lin, Hsieh, Kuo, Yu, Kuo, Lo, Lin, Yu, Li: Human TRIM71 and its nematode homologue are targets of let-7 microRNA and its zebrafish orthologue is essential for development. in Molecular biology and evolution 2007 (PubMed)

Weitere Antikörper gegen TRIM71 Interaktionspartner

Human Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) Interaktionspartner

TRIM71 acts through post-transcriptional repression of Lin28B and subsequent modulation of let-7-HMGA2 signaling during tumorigenesis to potentially function as a tumor suppressor.
Studies indicate most-studied TRIpartite Motif (TRIM (zeige TRAT1 Antikörper))-NHL (zeige RTEL1 Antikörper) proteins TRIM2 (zeige TRIM2 Antikörper), TRIM3 (zeige TRIM3 Antikörper), TRIM32 (zeige TRIM32 Antikörper) and TRIM71, and their mutations have been linked to diseases.
Consistent with the let-7 microRNA stimulatory role of TRIM71 via Lin28B (zeige LIN28B Antikörper) polyubiquitination.
The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing.
Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation
Repression of human TRIM71 and the zebrafish lin-41 ortholog was abolished when predicted let-7 target sites were mutated. Regulation of TRIM71 expression by let-7 seems to have been evolutionarily conserved.

Mouse (Murine) Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) Interaktionspartner

LIN41 interacts with p53 (zeige TP53 Antikörper), controls its abundance by ubiquitination and antagonizes p53 (zeige TP53 Antikörper)-dependent pro-apoptotic and pro-differentiation responses. In vivo, lack of LIN41 is associated with upregulation of Grhl3 (zeige GRHL3 Antikörper) and widespread caspase-3 (zeige CASP3 Antikörper) activation, 2 downstream effectors of p53 (zeige TP53 Antikörper) with essential roles in neural tube closure.
suggest that Trim71 keeps priming steps of differentiation in check, which do not pre-require a loss of the pluripotency network in ES cells
Two well-known E3 ubiquitin ligases, Trim25 (zeige TRIM25 Antikörper) (also called Efp (zeige TRIM25 Antikörper)) and Trim71 (also called Lin41), are validated as RNA-binding proteins, revealing a potential link between RNA biology and protein-modification pathways.
mLin41 acts as a temporal regulator to promote neural progenitor cell maintenance, not via the regulation of AGO2 (zeige EIF2C2 Antikörper) stability, but through FGF signaling.
Lin-41 is genetically and biochemically downstream of both the Shh (zeige SHH Antikörper) and Fgf signaling pathways and is expressed in three phases over developmental time and most notably is associated with the developing autopod.
lin-41 is temporally regulated by miRNAs in order to direct key developmental events such as limb formation.

TRIM71 Antigen-Profil

Beschreibung des Gens

May be involved in controlling the timing of organ formation during development (By similarity).

Alternative names and synonyms associated with TRIM71

tripartite motif containing 71 (TRIM71) Antikörper
tripartite motif containing 71 (Trim71) Antikörper
tripartite motif-containing 71 (Trim71) Antikörper

2610206G21Rik Antikörper
AL022943 Antikörper
Gm1127 Antikörper
lin-41 Antikörper
Lin41 Antikörper
mlin-41 Antikörper
mLin41 Antikörper
RGD1566388 Antikörper
Ripply2 Antikörper

Bezeichner auf Proteinebene für TRIM71

E3 ubiquitin-protein ligase TRIM71 , abnormal cell LINeage LIN-41 , homolog of C. elegans Lin-41 , protein lin-41 homolog , tripartite motif-containing 71 , tripartite motif-containing protein 71 , B-box zinc finger, Filamin and NHL repeat containing protein (123.8 kD) (lin-41) , Drosophila dappled/ vertebrate TRipartite Motif protein related , lin-41 homolog

GENE ID	SPEZIES
131405	Homo sapiens
477014	Canis lupus familiaris
531886	Bos taurus
301042	Rattus norvegicus
428445	Gallus gallus
636931	Mus musculus

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Show all anti-Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) Antikörper with Pubmed References

Human Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) Interaktionspartner

Mouse (Murine) Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with TRIM71

Bezeichner auf Proteinebene für TRIM71