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Human Monoclonal HEY1 Primary Antibody für IF, ELISA - ABIN525186
Tsuru, Setoguchi, Matsunoshita, Nagao-Kitamoto, Nagano, Yokouchi, Maeda, Ishidou, Yamamoto, Komiya: Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. in British journal of cancer 2015
Human Monoclonal HEY1 Primary Antibody für ELISA, WB - ABIN525187
Huang, Chu, Ye, Chen: Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum. in The Journal of biological chemistry 2014
Cow (Bovine) Polyclonal HEY1 Primary Antibody für IHC, WB - ABIN2779686
Meng, Su, Liu, Wang, Wang: Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2. in Neuroscience 2015
Simulation of HEY1 Ser (zeige SIGLEC1 Antikörper)-68 phosphorylation prevents its interaction with p53 (zeige TP53 Antikörper), RPL11 (zeige RPL11 Antikörper) and MDM2 (zeige MDM2 Antikörper) and abolishes HEY1 migration to nucleolar caps (zeige CAPS Antikörper) upon ribosomal stress. Our findings uncover a novel mechanism for cross-talk between Notch (zeige NOTCH1 Antikörper) signalling and nucleolar stress
Pancreatic involvement occurs in mesenchymal chondrosarcoma harboring the HEY1-NCOA2 (zeige NCOA2 Antikörper) gene fusion.
HGF (zeige HGF Antikörper)-induced FRA1 (zeige FOSL1 Antikörper) activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.
Expression of Hey1 induces translocation of FBXO45 (zeige FBXO45 Antikörper) into the nucleus.
Overexpression of HEY1 and HEY2 (zeige HEY2 Antikörper) in esophageal squamous cell carcinoma (ESCC) is correlated to different indices of poor prognosis, and it is extrapolated that such overexpression is important in progression and development of ESCC tumorigenesis.
bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 and Hey2 (zeige HEY2 Antikörper) gene expression within the first few hours after medium change
PML (zeige PML Antikörper) degradation mechanism through Notch (zeige NOTCH1 Antikörper)/Hey1-induced repression of the PML (zeige PML Antikörper) deubiquitinase USP11 (zeige USP11 Antikörper) involved in brain tumour pathogenesis
MMP9 (zeige MMP9 Antikörper) was a downstream effector of HEY1 that promotes the invasion of osteosarcoma cells. Knockdown of HEY1 decreased the expression of MMP9 (zeige MMP9 Antikörper).
In prostate tumors, the overexpression of PTOV1 (zeige PTOV1 Antikörper) was associated with decreased expression of HEY1 and HES1 (zeige HES1 Antikörper), and this correlation was significant in metastatic lesions.
a new HRD1 (zeige SYVN1 Antikörper)-associated membrane protein named HERP2, which is homologous to the previously identified HRD1 (zeige SYVN1 Antikörper) partner HERP1 (zeige HEY2 Antikörper). Despite sequence homology, HERP2 is constitutively expressed in cells, whereas HERP1 (zeige HEY2 Antikörper) is highly induced by ER stress.
A Jagged1 (zeige JAG1 Antikörper)-Hey1 signal might mediate the impairment of angiogenesis induced by Ang II (zeige AGT Antikörper) during cardiac hypertrophy.
Cyclic stretch enhanced the BMP-2induced osteoblastic differentiation through the inhibition of Hey1.
Hes (zeige ATCAY Antikörper)/Hey signaling at the Atoh1 (zeige ATOH1 Antikörper) promoter has a role in selection of cell fate in the organ of Corti
These in vitro and in vivo data support an anti-adipogenic role of COUP-TFII (zeige NR2F2 Antikörper) via downregulating the Notch (zeige NOTCH1 Antikörper) signaling target gene Hey1.
Hey proteins mechanistically repress target genes via histone deacetylase (zeige HDAC1 Antikörper) recruitment and histone deacetylation.
Hey1 and Hey2 (zeige HEY2 Antikörper) in endothelial cells play important roles in vascular development.
findings indicate that Hey1 and Hey2 (zeige HEY2 Antikörper) control the spatial and temporal pattern of auditory HC differentiation.
This study demonistrated that demonstrates that the lack of Hesr1 leads to an alteration in sensitivity to dopamine accompanied by enhanced prepulse inhibition.
A muscle-specific (zeige EIF3K Antikörper) regulatory element of p57(kip2 (zeige CDKN1C Antikörper)) directly activated by muscle regulatory factors in myoblasts but repressed by the Notch (zeige NOTCH1 Antikörper) targets Hes1 (zeige HES1 Antikörper)/Hey1 in progenitor cells, is identified.
Notch (zeige NOTCH1 Antikörper)-RBPjk (zeige RBPJ Antikörper) signaling functions in part through Hey1-mediated inhibition of NFATc1 (zeige NFATC1 Antikörper) to suppress osteoblastogenesis, contributing to bone homeostasis in vivo
abrogation of Hey1 function in adult pallial Neural stem cells in vivo, including quiescent Neural stem cells, leads to their differentiation without affecting their proliferation state.
Expression of seven hairy/E(spl (zeige SGPL1 Antikörper)) (her) genes is reported in three neurogenic areas of the adult zebrafish brain (telencephalon, hypothalamus, and midbrain) in relation to radial glia, proliferation, and neurogenesis.
hey1 represents a target of Delta-Notch (zeige NOTCH1 Antikörper) signaling dynamically expressed during somite formation in zebrafish
Results suggest that the negative regulatory loops between BMP/Tbx2 (zeige TBX2 Antikörper) and Gremlin (zeige GREM1 Antikörper) or Hey1 are responsible for defining the territory of the pronephric nephron.
HRT1 encodes a bhlh domain motif, a transcription repressor, which acts as an extended dimerization domain that contributes to the selection of partners.
XHRT1 plays an important role in glomerular development and early proximodistal patterning. [Xenopus HRT1]
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
HES-related repressor protein 1
, HES-related repressor protein 2
, basic helix-loop-helix protein OAF1
, cardiovascular helix-loop-helix factor 2
, class B basic helix-loop-helix protein 31
, hairy and enhancer of split-related protein 1
, hairy-related transcription factor 1
, hairy/enhancer-of-split related with YRPW motif protein 1
, bHLH protein Hesr-1/Hey1
, cardiovascular basic helix-loop-helix factor 2
, Hairy/E(spl)-related with YRPW motif 1
, basic helix-loop-helix transcription factor
, protein xbc8