Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) DEAF1 Antikörper:
anti-Human DEAF1 Antikörper:
anti-Rat (Rattus) DEAF1 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
The sex dependence of Deaf1 function in mice is consistent with a greater role for 5-HT1A (zeige HTR1A Antikörper) autoreceptors in sensitivity to depression in men.
These data suggest that during the progression of type 1 diabetes, inflammation and hyperglycemia mediate the splicing of DEAF1 and loss of peripheral tissue antigen expression.
DEAF1 binds to the IFNbeta promoter and to IRF3 and IRF7, that it is required for the transcription of the IFNbeta gene and IFNbeta secretion
reduced DEAF1 function, and subsequent loss of Eif4g3 transcription may affect peripheral tissue antigen (PTA) expression in LNSCs and contribute to the pathology of T1D.
LMO4 (zeige LMO4 Antikörper) modulates the activity of the DEAF NES (zeige NES Antikörper), causing nuclear accumulation of a construct containing the LMO4 (zeige LMO4 Antikörper)-interaction region of DEAF1.
Reduced raphe 5-HT (zeige DDC Antikörper) content in Deaf-1(-/-) mice indicate its importance in regulation of 5-HT1A (zeige HTR1A Antikörper) gene expression and the role of the 5-HT1A (zeige HTR1A Antikörper) G(-1019) allele in reducing serotonergic neurotransmission by derepression of 5-HT1A (zeige HTR1A Antikörper) autoreceptors.
These results suggest that transcription factors such as Aire and Deaf1, which exert global transcriptional regulatory functions, may play important roles in self-renewal of ESCs and maintaining ESC in a transcriptionally hyperactive state.
Data indicate an important role for LMO4 (zeige LMO4 Antikörper) and Deaf-1 in pathways affecting neural tube closure and skeletal patterning, most likely reflecting their presence in a functional complex in vivo.
Lower peripheral tissue antigens (PTA (zeige PTCRA Antikörper)) expression resulting from the alternative splicing of DEAF1 may contribute to the pathogenesis of type 1 diabetes.
The results demonstrate that variants located within the neurodevelopmental disorder (DAND)or NLS (zeige ALDH1A2 Antikörper) domains significantly reduce DEAF1 transcriptional regulatory activities and are thus, likely to contribute to the underlying clinical concerns in DAND patients.
identified pathogenic de novo variants in two cases, a nonsense variant in IQSEC2 (zeige IQSEC2 Antikörper) and a missense variant in the SAND domain of DEAF1
We conclude that this DEAF1 gene alteration caused this patient's symptoms and that white matter disease should not be considered a obligate feature of this syndrome.
RAI1 (zeige DOM3Z Antikörper) polymorphisms rs4925102 and rs9907986 are predicted to disrupt the binding of retinoic acid RXR-RAR (zeige RARA Antikörper) receptors and the transcription factor DEAF1, respectively, in Smith-Magenis and Potocki-Lupski syndromes patients.
an autosomal recessive splice acceptor mutation in DEAF1 (c.997+4A>C, p.G292Pfs*) in all affected individuals, which led to exon skipping, and reduced the normal full-length mRNA copy number in the patients with epilepsy and extrapyramidal symptoms
Data show that deformed epidermal autoregulatory factor-1 (DEAF1) was located in the nucleus under the fluorescence microscope.
This study indicates, for the first time, a hereditary role of DEAF1 in white matter abnormalities, microcephaly and syndromic intellectual disability.
these results demonstrate that mutations in DEAF1 cause ID and behavioral problems, most likely as a result of impaired transcriptional regulation by DEAF1.
Pellino1 interacts with the transcription factor Deformed Epidermal Autoregulatory Factor 1 (DEAF1).
effects of loss or gain of DEAF-1 function on Drosophila development
DEAF-1 is a regulator of Drosophila immunity; it activates the expression of Mtk and Drs (zeige DARS Antikörper) promoter.
Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd.
deformed epidermal autoregulatory factor 1 homolog
, nuclear DEAF-1-related transcriptional regulator
, zinc finger MYND domain-containing protein 5
, nuclear DEAF-1 related transcriptional regulator
, zinc finger MYND domain containing 5
, DEAF-1 related transcriptional regulator
, DEAF-1 related transcriptional regulator (NUDR)
, deformed epidermal autoregulatory factor 1 (Drosophila)
, deformed epidermal autoregulatory factor 1 homolog-like
, deformed epidermal autoregulatory factor 1
, deformed epidermal autoregulatory factor-1