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TNFSF13 Proteine

(Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].

46 Treffer

TNFSF13 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining PI, STD, Func, AbP Active
Produktnummer ABIN2713553
401,85 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
20 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 11 Werktagen
 
TNFSF13 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3012086
962,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 7 bis 15 Werktagen
 
TNFSF13 Spezies: Affe Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3012087
1.095,97 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 7 bis 15 Werktagen
 
TNFSF13 Spezies: Hund Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3012085
1.112,65 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 7 bis 15 Werktagen
 
MALS verified TNFSF13 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN7121166
528,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 9 bis 11 Werktagen
 
TNFSF13 Spezies: Human Wirt: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. SDS, WB, ELISA, MS
Produktnummer ABIN7314174
2.523,08 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 5 bis 6 Werktagen
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Immunoprecipitation (IP)
    • Activity Assay (AcA)
    • Affinity Measurement (AM)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Cell Culture (CC)
    • Functional Studies (Func)
    • Immunoassay (IA)
    • Mass Spectrometry (MS)
    • Multiplex Assay (MA)
    • Protein Interaction (PI)
    • Screening Assay (ScA)
    • Standard (STD)
    • Antibody Drug Assay (ADA)
  • Reaktivität
    • Human
    • Mouse
    • Cynomolgus
    • Dog
    • Rat
    • Cow
    • Monkey
    • Rhesus Monkey
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • Human Cells
    • CHO Cells
    • Hi-5 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 112-250
    • Trimer
    • AA 96-241
    • AA 105-250
    • AA 96-240
    • AA 16-108
    • AA 18-111
    • AA 1-247
    • AA 105-247
    • AA 111-250
    • AA 50-241
    • AA 88-232
    • AA 88-233
    • AA 92-250
    • AA 93-250
    • AA 98-232
    • AA 98-233
    • AA 99-330
    • N-Term
    • Transcript Variant 1
  • Konjugat
    • His tag
    • Unkonjugiert
    • DYKDDDDK Tag
    • Fc Tag
    • His-DYKDDDDK Tag
    • Biotin,His-Avi-DYKDDDDK Tag
    • His tag,DYKDDDDK Tag
    • His-Avi-DYKDDDDK Tag
    • Biotin,His-DYKDDDDK Tag
    • DYKDDDDK-His Tag
    • Fc Tag,AVI tag,Biotin
    • GST tag
    • T7 tag
    • hFc Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • Abbexa
    • BioLegend
    • Cohesion Biosciences
    • OriGene

Aktuelle Publikationen für unsere TNFSF13 Proteine

Rodríguez-Bayona, Ramos-Amaya, López-Blanco, Campos-Caro, Brieva: "STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 4996-5004, (2013) (PubMed).

Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).

Chihara, Aranami, Sato, Miyazaki, Miyake, Okamoto, Ogawa, Toda, Yamamura: "Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 9, pp. 3701-6, (2011) (PubMed).

Sakurai, Hase, Kanno, Kojima, Okumura, Kobata: "TACI regulates IgA production by APRIL in collaboration with HSPG." in: Blood, Vol. 109, Issue 7, pp. 2961-7, (2007) (PubMed).

Endo, Nishio, Enzler, Cottam, Fukuda, James, Karin, Kipps: "BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway." in: Blood, Vol. 109, Issue 2, pp. 703-10, (2007) (PubMed).

Mongini, Inman, Han, Fattah, Abramson, Attur: "APRIL and BAFF promote increased viability of replicating human B2 cells via mechanism involving cyclooxygenase 2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 11, pp. 6736-51, (2006) (PubMed).

Craxton, Draves, Gruppi, Clark: "BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway." in: The Journal of experimental medicine, Vol. 202, Issue 10, pp. 1363-74, (2005) (PubMed).

Bonci, Hahne, Felli, Peschle, De Maria: "Potential role of APRIL as autocrine growth factor for megakaryocytopoiesis." in: Blood, Vol. 104, Issue 10, pp. 3169-72, (2004) (PubMed).

He, Chadburn, Jou, Schattner, Knowles, Cerutti: "Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 5, pp. 3268-79, (2004) (PubMed).

Litinskiy, Nardelli, Hilbert, He, Schaffer, Casali, Cerutti: "DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL." in: Nature immunology, Vol. 3, Issue 9, pp. 822-9, (2002) (PubMed).

Aliase für TNFSF13 Proteine

TNF superfamily member 13 (TNFSF13) Proteine
tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13) Proteine
acidic leucine-rich nuclear phosphoprotein 32 family member B (LOC494442) Proteine
tumor necrosis factor (ligand) superfamily, member 13 (tnfsf13) Proteine
TNF superfamily member 13 (Tnfsf13) Proteine
tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13) Proteine
2310026N09Rik Proteine
ANP32B Proteine
APRIL Proteine
April Proteine
april Proteine
CD256 Proteine
SLAN Proteine
TALL-2 Proteine
TALL2 Proteine
Tall2 Proteine
tnf13 Proteine
TNLG7B Proteine
TRDL-1 Proteine
Trdl1 Proteine
ZTNF2 Proteine
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