TNFRSF4 Proteine
(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008].
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TNFRSF4
Spezies: Kaninchen
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
TNFRSF4
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
TNFRSF4
Spezies: Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB, ELISA
Active
TNFRSF4
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB, ELISA
Active
TNFRSF4
Spezies: Human
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
TNFRSF4
Spezies: Kaninchen
Wirt: HEK-293 Cells
Recombinant
>85 % as determined by SDS-PAGE.
WB
TNFRSF4
Spezies: Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB, ELISA
Active
TNFRSF4
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>92 % as determined by SDS-PAGE.
WB
TNFRSF4
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB
TNFRSF4
Spezies: Cynomolgus, Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Aktuelle Publikationen für unsere TNFRSF4 Proteine
: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." in: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).
: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).
Aliase für TNFRSF4 Proteine
TNF receptor superfamily member 4 (TNFRSF4) Proteinetumor necrosis factor receptor superfamily, member 4 (Tnfrsf4) Proteine
TNF receptor superfamily member 4 (Tnfrsf4) Proteine
ACT35 Proteine
CD134 Proteine
Ly-70 Proteine
Ox40 Proteine
OX40 Proteine
TNFRSF4 Proteine
Txgp1 Proteine
TXGP1L Proteine
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