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anti-Human TNFAIP3 Antikörper:
anti-Mouse (Murine) TNFAIP3 Antikörper:
anti-Rat (Rattus) TNFAIP3 Antikörper:
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Human Monoclonal TNFAIP3 Primary Antibody für CyTOF, FACS - ABIN4277015
Kupfner, Arcaroli, Yum, Nadler, Yang, Abraham: Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 38 Pubmed References
Low A20 expression is associated with hepatocellular carcinoma.
The results suggest that TNFAIP3 polymorphisms (rs2230926, rs5029937, rs5029939, and rs3757173) are associated with susceptibility to systemic lupus erythematosus. (Meta-analysis)
Hepatitis C virus core protein ligates gC1qR (zeige C1QBP Antikörper) to induce A20 expression in macrophages via P38 (zeige CRK Antikörper), JNK (zeige MAPK8 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) signaling pathways, which leads to a low-grade chronic inflammation during HCV infection.
Results show that TNFAIP3 expression is regulated by miR (zeige MLXIP Antikörper)-19b through targeting its 3'-UTR (zeige UTS2R Antikörper) which contributes to the radioresistance of nasopharyngeal carcinoma and consequently activating the NF-kappaB (zeige NFKB1 Antikörper) pathway.
demonstrates that TNFAIP3 gene polymorphisms (rs2230926 and rs5029937) are associated with the increased risk of rheumatoid arthritis. [META-ANALYSIS]
CHN1 and TNFAIP3 are candidate biomarkers for esophageal squamous cell carcinomas
These results identify the ubiquitin-editing enzyme A20 as a novel endogenous mechanism for negative regulation of fibrotic response intensity
Our data propose an additional novel mechanism to explain the known NF-kappaB inhibitory effects of A20: by affecting p105 ubiquitination and subsequently its degradation and limited processing.
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1 (zeige SNAI1 Antikörper).
Low TNFAIP3 expression is associated with colitis-associated colorectal cancer.
Tnfaip3, an anti-inflammatory gene, is located precisely underneath the linkage peak and contains two non-synonymous SNPs leading to conservative amino acid substitutions.
These results suggest that Leishmania exploits A20 and UCP2 (zeige UCP2 Antikörper) to impair inflammasome activation for disease propagation
holding thymic production of natural Treg cells in check, A20 integrates Treg cell activity and increased effector T cell survival into an efficient CD4 (zeige CD4 Antikörper)(+) T cell response
these studies establish A20 as a crucial hepatoprotective factor.
These results suggested that A20 is involved in regulating intracerebral hemorrhage-induced inflammatory injury in both the central and peripheral system
the ubiquitin-modifying enzyme TNFAIP3/A20, an upstream regulator of T cell receptor (TCR) signaling in T cells, is an essential cell-intrinsic regulator of Natural killer T differentiation.
these data reveal a crucial role of A20 in regulating the immunomodulatory activities of mesenchymal stem cells.
Therefore, A20 acts as a novel endogenous regulator of STAT1 (zeige STAT1 Antikörper) that prevents onset of enthesitis.
Data show the characterization and deduced amino acid sequence analysis for A20 gene which expression increases in MDBK cells infected by BVDV-1. Also, regulatory regions for NF-kappaB (zeige NFKB1 Antikörper) and Sp-1 (zeige SP1 Antikörper) additionally to an ARE element for mRNA stability were detected
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
tumor necrosis factor, alpha-induced protein 3
, OTU domain-containing protein 7C
, TNF alpha-induced protein 3
, putative DNA-binding protein A20
, tumor necrosis factor alpha-induced protein 3
, tumor necrosis factor inducible protein A20
, zinc finger protein A20
, tumor necrosis factor induced protein 3