TLR4 Proteine
(Toll-Like Receptor 4 (TLR4))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Aktuelle Publikationen für unsere TLR4 Proteine
: "CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2015) (PubMed).: "Analysis of mechanistic pathway models in drug discovery: p38 pathway." in: Biotechnology progress, Vol. 24, Issue 1, pp. 96-109, (2008) (PubMed).
Aliase für TLR4 Proteine
toll like receptor 4 (TLR4) Proteinetoll-like receptor 4 (Tlr4) Proteine
toll like receptor 4 (Tlr4) Proteine
ARMD10 Proteine
CD284 Proteine
Lps Proteine
Ly87 Proteine
Ran/M1 Proteine
Rasl2-8 Proteine
TLR-4 Proteine
TOLL Proteine
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