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Thyroperoxidase Proteine

(Thyroid Peroxidase (TPO))
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

15 Treffer :

TPO Spezies: Human Wirt: Human Native > 95 % pure
Pubmed 2 Referenzen Independent Validation 2 validations
Produktnummer ABIN934717
Independently Validated
TPO Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275771
 
TPO Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275772
 
TPO Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Produktnummer ABIN1323444
 
TPO Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Produktnummer ABIN1323443
 
TPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Produktnummer ABIN7402157
 
TPO Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7390964
 
TPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Produktnummer ABIN7402250
 
TPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Produktnummer ABIN7390967
 
TPO Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7390970
 
TPO Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7198245
 
TPO Spezies: Human Wirt: Insektenzellen Recombinant > 95 % pure (SDS PAGE) EIA
Produktnummer ABIN573540
 
TPO Spezies: Human Wirt: Insect cells (Sf9) Recombinant > 95 % pure WB, ELISA
Produktnummer ABIN2132174
 
TPO Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant 90 % WB, ELISA
Produktnummer ABIN7479631
 
TPO Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2733688
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • SDS-PAGE (SDS)
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Enzyme Immunoassay (EIA)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Independent Validation
  • Preservative free only
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • Human
    • Insect Cells
    • Insect cells (Sf9)
  • Bindungsspezifität
    • AA 19-846
    • AA 1-933
    • AA 107-276
    • AA 22-194
    • AA 32-834
    • AA 39-217
    • AA 402-558
    • AA 636-832
    • AA 672-779
    • Transcript Variant 1
    • full length
  • Konjugat
    • His tag
    • GST tag
    • Unkonjugiert
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
    • Native
  • Format
    • Lyophilized
    • Liquid
  • Hersteller
    • antibodies-online
    • CUSABIO
    • OriGene

Aktuelle Publikationen für unsere Thyroperoxidase Proteine

Ali, Wolfe, Mukherjee, Radford, Patel, White, Milojevic, Capretta, Nair, Brennan: "A sputum bioassay for airway eosinophilia using an eosinophil peroxidase aptamer." in: Scientific reports, Vol. 12, Issue 1, pp. 22476, (2022) (PubMed).

Eick, Cepon-Robins, Devlin, Kowal, Sugiyama, Snodgrass: "Development and validation of an ELISA for a biomarker of thyroid dysfunction, thyroid peroxidase autoantibodies (TPO-Ab), in dried blood spots." in: Journal of physiological anthropology, Vol. 39, Issue 1, pp. 16, (2020) (PubMed).

Rahnama, Mahmoudi, Kazemnejad, Salehi, Ghahiri, Soltanghoraee, Vafaei, Rezaei, Zarnani: "Thyroid peroxidase in human endometrium and placenta: a potential target for anti-TPO antibodies." in: Clinical and experimental medicine, (2020) (PubMed).

Zhou, Wang, Zhao, Liu, Zhao, Zhang, Shan, Teng: "Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice." in: Frontiers in cellular neuroscience, Vol. 10, pp. 307, (2017) (PubMed).

Aliase für Thyroperoxidase Proteine

thyroid peroxidase (TPO) Proteine
thyroid peroxidase (Tpo) Proteine
thyroid peroxidase (tpo) Proteine
thyroid peroxidase (LOC100547103) Proteine
LOC100218312 Proteine
MSA Proteine
msa Proteine
TDH2A Proteine
TPO Proteine
TPX Proteine
tpx Proteine
xtpo Proteine
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