THO Complex 5 Produkte
(THO Complex 5 (THOC5))
Kategorien
Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in the differentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays an integral role in monocytic development (By similarity).
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Ausgewählte THO Complex 5 Kategorien
THO Complex 5 Antikörper
High quality antibodies with extensive validation data.
THO Complex 5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene THO Complex 5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7172059
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IF, ICC
Validierungen
- (1)
Kat. Nr.
ABIN6265558
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN6149119
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene THO Complex 5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6207985
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene THO Complex 5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1322701
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3095926
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3136208
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren THO Complex 5 Produkten
: "mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3." in: Nature communications, Vol. 6, pp. 8192, (2015) (PubMed).: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).
Synonyme und alternative Namen zu THO Complex 5
THO complex 5 (THOC5), THO complex 5 (Thoc5), THO complex 5 (thoc5), THO complex 5 S homeolog (thoc5.S), THO complex 5 L homeolog (thoc5.L), 1700060C24Rik, A430085L24Rik, C22orf19, fc54b09, Fmip, fmip, fSAP79, PK1.3, Sgk2, THOC5, thoc5, thoc5-a, thoc5-b, wu:fc54b09, zgc:56190, zgc:76912Bezeichner auf Proteinebene für THO Complex 5
- Fms-interacting protein
- NF2/meningioma region protein pK1.3
- PP39.2
- THO complex subunit 5 homolog
- functional spliceosome-associated protein 79
- hTREX90
- placental protein 39.2
- Fms interacting protein
- fms-interacting protein
- serum/glucocorticoid regulated kinase 2
- protein C22orf19
- THO complex 5
- THO complex subunit 5 homolog-like
- THO complex subunit 5 homolog B
- THO complex subunit 5 homolog A
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