TFF1 Proteine
(Trefoil Factor 1 (TFF1))
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008].
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Aktuelle Publikationen für unsere TFF1 Proteine
: "Proteolytic effects of gingipains on trefoil factor family peptides." in: Clinical oral investigations, Vol. 22, Issue 2, pp. 1009-1018, (2018) (PubMed).: "High trefoil factor 1 (TFF1) expression in human retinoblastoma cells correlates with low growth kinetics, increased cyclin-dependent kinase (CDK) inhibitor levels and a selective down-regulation of ..." in: Histochemistry and cell biology, Vol. 139, Issue 2, pp. 323-38, (2014) (PubMed).
: "Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous ..." in: Digestive diseases and sciences, Vol. 56, Issue 12, pp. 3498-506, (2011) (PubMed).
: "The aurora kinase A regulates GSK-3beta in gastric cancer cells." in: Oncogene, Vol. 28, Issue 6, pp. 866-75, (2009) (PubMed).
Aliase für TFF1 Proteine
trefoil factor 1 (TFF1) Proteinetrefoil factor 1 (Tff1) Proteine
trefoil factor 1 S homeolog (tff1.S) Proteine
trefoil factor 1, gene 2 S homeolog (tff1.2.S) Proteine
trefoil factor 1 (LOC100358238) Proteine
BCEI Proteine
Bcei Proteine
bcei Proteine
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d21s21 Proteine
HP1.A Proteine
hp1.a Proteine
HPS2 Proteine
hps2 Proteine
p1 Proteine
p1-a Proteine
pNR-2 Proteine
pnr-2 Proteine
pS2 Proteine
PS2 Proteine
ps2 Proteine
Ps2 Proteine
tff1 Proteine
TFF1 Proteine
xP1 Proteine
xp1 Proteine
xp1-L Proteine
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