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anti-Human MALT1 Antikörper:
anti-Mouse (Murine) MALT1 Antikörper:
anti-Rat (Rattus) MALT1 Antikörper:
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Human Monoclonal MALT1 Primary Antibody für IHC (p), WB - ABIN2475476
Pincus, Kahan, Mittal: A role for cAMP in the preparation of human platelets for the extraction of histocompatibility antigens. in Immunochemistry 1976
Show all 3 Pubmed References
Mouse (Murine) Polyclonal MALT1 Primary Antibody für ELISA, WB - ABIN4332478
Rosebeck, Madden, Jin, Gu, Apel, Appert, Hamoudi, Noels, Sagaert, Van Loo, Baens, Du, Lucas, McAllister-Lucas: Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. in Science (New York, N.Y.) 2011
A missense mutation in mucosa-associated lymphoid tissue lymphoma translocation 1 gene (MALT1) was identified in a family with siblings with IPEX (zeige FOXP3 Antikörper)-Like Syndrome. MALT1 deficiency should now be considered as a possible cause of IPEX (zeige FOXP3 Antikörper)-like syndrome associated with immunodeficiency.
Thrombin (zeige F2 Antikörper)-mediated MALT1 protease activation triggers acute disruption of endothelial barrier integrity via CYLD (zeige CYLD Antikörper) cleavage.
Authors utilized transcriptomic data and experimental evidences to prove that miR (zeige MLXIP Antikörper)-181d was a novel regulator of NFkappaB (zeige NFKB1 Antikörper) signaling pathway by directly repressing MALT1, leading to induced PN markers and reduced MES (zeige ME1 Antikörper) genes.
Taken together, this present study indicates that miR (zeige MLXIP Antikörper)-649 promotes herpes simplex virus type 1 replication through regulation of the MALT1-mediated antiviral signaling pathway and suggests a promising target for antiviral therapies.
These results demonstrate a key role for the proteolytic activity of MALT1 in PEL, and provide a rationale for the pharmacological targeting of MALT1 in PEL therapy.
MALT1 deficiency or pharmacological inhibition of MALT1 catalytic activity inhibits pathogenic mutant CARD14 (zeige CARD14 Antikörper)-induced cytokine and chemokine (zeige CCL1 Antikörper) expression in human primary keratinocytes.
results unveil HOIL1 (zeige RBCK1 Antikörper) as a negative regulator of lymphocyte activation cleaved by MALT1.
CARD14 (zeige CARD14 Antikörper)/MALT1-mediated signaling in keratinocytes has a role in psoriasis [review]
Psoriasis mutations disrupt CARD14 (zeige CARD14 Antikörper) autoinhibition promoting BCL10 (zeige BCL10 Antikörper)-MALT1-dependent NF-kappaB (zeige NFKB1 Antikörper) activation
Studies indicate that t(11;18)(q21;q21) translocation involves MALT1 (MALT lymphoma translocation protein 1) gene.
Data show that inhibition of the protease activity of MALT1 might be a strategy to treat inflammatory bowel disease and the NLRP3 (zeige NLRP3 Antikörper) inflammasome and NF-kappaB (zeige NFKB1 Antikörper) activation are critical components in MALT1 signaling cascades in this disease model.
MALT1 function is required in B cells for germinal center formation.
Studies indicate an important role for mucosa associated lymphoid tissue lymphoma translocation gene 1 protein (MALT1) in the development of experimental autoimmune encephalomyelitis (EAE)
Targeting MALT1 proteolytic activity in autoimmune disease and B-cell lymphoma might not be a successful strategy. (Review)
TCR-induced alternative splicing augments MALT1 scaffolding to enhance downstream signalling and to promote optimal T-cell activation.
MALT1-dependent NF-kappaB (zeige NFKB1 Antikörper) activation is crucial for the development of EGFR (zeige EGFR Antikörper)-associated solid-tumor progression
By regulating linear ubiquitination, MALT1 is both a positive and negative pleiotropic regulator of the canonical NF-kappaB (zeige NFKB1 Antikörper) pathway.
Results demonstrate that MALT1 protease activity plays key roles in both innate and adaptive immune responses, and in regulating immune homeostasis in vivo.
data demonstrate that MALT1 ubiquitination is critical for the engagement of CBM and IKK (zeige CHUK Antikörper) complexes, thereby directing platelet signals to the NF-kappaB (zeige NFKB1 Antikörper) pathway.
This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
mucosa associated lymphoid tissue lymphoma translocation gene 1
, mucosa associated lymphoid tissue lymphoma translocation protein 1
, mucosa-associated lymphoid tissue lymphoma translocation protein 1-like
, MALT associated translocation
, MALT lymphoma-associated translocation
, MALT-lymphoma associated translocation
, caspase-like protein
, mucosa-associated lymphoid tissue lymphoma translocation protein 1
, mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog