anti-Gephyrin (GPHN) Antikörper

Bezeichnung:: anti-Gephyrin Antikörper (GPHN)

Auf www.antikoerper-online.de finden Sie aktuell 84 Gephyrin (GPHN) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Gephyrin Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 94 Gephyrin Produkte verfügbar.

Synonyme:: 5730552E08Rik, AI662856, BC027112, C230040D23, DKFZp459M0825, GEPH, gpgb1, GPH, GPHN, GPHRYN, HKPX1

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	GPHN	268566	Q8BUV3
	GPHN	64845	Q03555
	GPHN	10243	Q9NQX3
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Gephyrin (GPHN) Antikörper

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anti-Mouse (Murine) Gephyrin Antikörper:

anti-Rat (Rattus) Gephyrin Antikörper:

anti-Human Gephyrin Antikörper:

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Verknüpfte Pathways mit anti-Gephyrin Antikörper

Weitere Produktkategorien zu Gephyrin Antikörper

Am meisten referenzierte anti-Gephyrin Antikörper

Chicken Monoclonal Gephyrin Primary Antibody für IF, IP - ABIN968051 : Feng, Tintrup, Kirsch, Nichol, Kuhse, Betz, Sanes: Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. in Science (New York, N.Y.) 1998 (PubMed)
Show all 4 Pubmed References
Chicken Monoclonal Gephyrin Primary Antibody für IF, IP - ABIN968050 : Meyer, Kirsch, Betz, Langosch: Identification of a gephyrin binding motif on the glycine receptor beta subunit. in Neuron 1995 (PubMed)
Show all 4 Pubmed References
Chicken Monoclonal Gephyrin Primary Antibody für IF, IP - ABIN968898 : Prior, Schmitt, Grenningloh, Pribilla, Multhaup, Beyreuther, Maulet, Werner, Langosch, Kirsch: Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein. in Neuron 1992 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen Gephyrin Interaktionspartner

Mouse (Murine) Gephyrin (GPHN) Interaktionspartner

Ablation of gephyrin result in the forebrain-specific loss of postsynaptic gamma2-GABAA (zeige GABRg1 Antikörper) receptors, reduces LTP (zeige SCP2 Antikörper) and network excitability in the dentate gyrus.
adult mice lacking interleukin-1 receptor 1 (zeige IL1RL1 Antikörper) (IL-1R1) exhibit increased expression of both the excitatory scaffolding protein postsynaptic density-95 (PSD-95 (zeige DLGAP2 Antikörper)) and inhibitory scaffolding proteingephyrin, respectively, in the hippocampus.
The results demonstrate that formation of GABAergic synapses containing a postsynaptic gephyrin scaffold is crucial for morphological differentiation, synaptic integration, and long-term survival of adult-born granule cells/
Data suggest that KIF5 regulates gephyrin sorting by a mechanism that involves GSK3 activity.
Pin1 (zeige PIN1 Antikörper)-dependent signaling represents a mechanism to modulate GABAergic transmission by regulating NL2 (zeige MMEL1 Antikörper)/gephyrin interaction.
These results reveal a homeostatic mechanism through which activity regulates the dynamics and function of perisomatic inhibitory synapses, and they identify a CaMKII (zeige CAMK2G Antikörper)-dependent phosphorylation site on gephyrin.
study reveals that palmitoylation of gephyrin by DHHC-12 contributes to dynamic and functional modulation of GABAergic synapses
Within this network, collybistin (zeige Arhgef9 Antikörper) can adopt open/active and closed/inactive conformations to act as a switchable adaptor that links gephyrin to plasma membrane phosphoinositides.
these findings suggest that gephyrin may be a key factor in BDNF (zeige BDNF Antikörper)-dependent GABAAR (zeige GABRG2 Antikörper) regulation in the amygdala.
Data suggest that the loss of neurotransmitter receptor (zeige GRIN1 Antikörper) clustering at inhibitory synapses causes the early lethality of gephyrin deficient mice.

Human Gephyrin (GPHN) Interaktionspartner

This study shown that the SNPs located in the rs723432 (Pallele=0.007; uncorrected) in the GPHN gene showed associated with Japanese individuals affected with schizophrenia.
these data reveal that IQSEC3 (zeige IQSEC3 Antikörper) acts together with gephyrin to regulate inhibitory synapse development.
A missense mutation of gephyrin that was unable to synthesize MoCo and activate MoCo-dependent enzymes was identified.
A yin-yang haplotype pattern encompassing gephyrin consists of 284 divergent nucleotide states and both variants vary drastically from their mutual ancestral haplotype, suggesting rapid evolution.
The N-terminal region of GABRA3 (zeige GABRA3 Antikörper) and the GlyR beta subunit (zeige POLG Antikörper) occupies the same binding site of gephyrin.
Results show that PKC (zeige PRRT2 Antikörper)-dependent phosphorylation of GAP43 (zeige GAP43 Antikörper) plays a critical role in regulating postsynaptic gephyrin aggregation in developing GABAergic synapses.
Structural exonic microdeletions affecting the GPHN gene constitute a rare genetic risk factor for IGE and other neuropsychiatric disorders by an impairment of the GABAergic inhibitory synaptic transmission.
The enhancement of Cb-induced gephyrin clustering by GTP (zeige AK3 Antikörper)-TC10 (zeige RHOQ Antikörper) does not depend on the guanine nucleotide exchange activity of Cb but involves an interaction that resembles reported interactions of other small GTPases with their effectors
abnormal accumulations of gephyrin are highly correlated with the neuropathologic diagnosis of Alzheimer disease in 17 AD versus 14 control cases. Furthermore, gephyrin accumulations were specific for AD.
Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures.

Zebrafish Gephyrin (GPHN) Interaktionspartner

duplicated gephyrin genes mediate Moco biosynthesis and control postsynaptic clustering of glycine receptor (zeige GLRB Antikörper)

Gephyrin (GPHN) Antigen-Profil

Beschreibung des Gens

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described\; however, the full-length nature of all transcript variants is not currently known.

Alternative names and synonyms associated with Gephyrin (GPHN)

gephyrin (Gphn) Antikörper
gephyrin (GPHN) Antikörper
gephyrin L homeolog (gphn.L) Antikörper
gephyrin a (gphna) Antikörper
gephyrin (PTRG_08978) Antikörper
gephyrin (VDBG_00775) Antikörper
gephyrin (Tsp_03043) Antikörper
gephyrin (gphn) Antikörper

5730552E08Rik Antikörper
AI662856 Antikörper
BC027112 Antikörper
C230040D23 Antikörper
DKFZp459M0825 Antikörper
GEPH Antikörper
gpgb1 Antikörper
GPH Antikörper
GPHN Antikörper
GPHRYN Antikörper
HKPX1 Antikörper

Bezeichner auf Proteinebene für anti-Gephyrin (GPHN) Antikörper

gephyrin isoform , putative glycine receptor-tubulin linker protein , gephyrin , gephyrin1 , gephyrin-like , LOW QUALITY PROTEIN: gephyrin

GENE ID	SPEZIES
268566	Mus musculus
64845	Rattus norvegicus
100063078	Equus caballus
709677	Macaca mulatta
452976	Pan troglodytes
779372	Xenopus laevis
428878	Gallus gallus
490739	Canis lupus familiaris
10243	Homo sapiens
535194	Bos taurus
555470	Danio rerio
6347264	Pyrenophora tritici-repentis Pt-1C-BFP
9530667	Verticillium alfalfae VaMs.102
10900320	Trichinella spiralis
100022949	Monodelphis domestica
100124966	Xenopus (Silurana) tropicalis
100153443	Sus scrofa
100172899	Pongo abelii
100396072	Callithrix jacchus
100471953	Ailuropoda melanoleuca
100555683	Anolis carolinensis
100715524	Cavia porcellus
100338344	Oryctolagus cuniculus

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