anti-AKR1C2 (AKR1C2) Antikörper

Bezeichnung:: anti-Aldo-keto Reductase Family 1, Member C2 Antikörper (AKR1C2)

Auf www.antikoerper-online.de finden Sie aktuell 73 Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen AKR1C2 Proteine (9) und AKR1C2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 102 AKR1C2 Produkte verfügbar.

Synonyme:: AKR1C-pseudo, Akr1c21, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	AKR1C2	1646	P52895
	AKR1C2	291283	Q6AYQ2
	AKR1C2
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Rat (Rattus) AKR1C2 Antikörper:

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Am meisten referenzierte anti-AKR1C2 Antikörper

Human Monoclonal AKR1C2 Primary Antibody für ELISA, WB - ABIN514927 : Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro. in Drug metabolism and disposition: the biological fate of chemicals 2008 (PubMed)
Show all 2 Pubmed References
Human Polyclonal AKR1C2 Primary Antibody für WB - ABIN514925 : Ebert, Kisiela, Wsól, Maser: Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29. in Chemico-biological interactions 2011 (PubMed)
Human Polyclonal AKR1C2 Primary Antibody für ELISA, WB - ABIN560582 : Su, Liao, Huang, Chu, Lin, Chang: Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis. in Toxicology 2008 (PubMed)

Weitere Antikörper gegen AKR1C2 Interaktionspartner

Human Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Interaktionspartner

Data show that increased levels of AKR1C1 (zeige DDH Antikörper)/C2 enhanced the sensitivity of esophageal squamous cell carcinoma (ESCC) cells to ethyl-3,4-dihydroxybenzoate (EDHB).
The reduction of DHT obese homozygotic twins could be linked to its increased degradation by AKR1C2 and HSD11B1 (zeige HSD11B1 Antikörper), and increased estrogen levels could be linked to increased adiposity-related expression of aromatase (zeige CYP19A1 Antikörper) in adipose tissue.
the present study suggests that AKR1C1 (zeige DDH Antikörper), AKR1C2, AKR1C3 (zeige AKR1C3 Antikörper), and AKR1C4 (zeige AKR1C4 Antikörper) are closely associated with drug resistance to both CDDP and 5FU, and that mefenamic acid, an inhibitor of AKR1C, restores sensitivity through inhibition of drug-resistance in human cancer cells.
We identified two powerful genes in the liver cancer metastasis process, AEG-1 (zeige MTDH Antikörper) and AKR1C2.
Identify two novel factors, AKR1C2 (positive factor) and NF1 (zeige NF1 Antikörper) (negative factor), as the AEG-1 (zeige MTDH Antikörper) downstream players in the process of metastasis in liver cancer.
The endogenous HMOX1 (zeige HMOX1 Antikörper) gene but not the AKR1C2 gene is strongly repressed by Bach1 (zeige BACH1 Antikörper) in HaCaT keratinocytes.
In model cell lines of endometrial cancer, AKR1C2 and SRD5A1 (zeige SRD5A1 Antikörper) have crucial roles in progesterone metabolism.
Significantly higher levels of SRD5A1 (zeige SRD5A1 Antikörper), AKR1C2, AKR1C3 (zeige AKR1C3 Antikörper), and HSD17B10 (zeige HSD17B10 Antikörper) mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue
The V54L mutation significantly decreases the 3alpha-hydroxysteroid dehydrogenase activity of DDH2 for the reduction of dihydrotestosterone.
DDH2 expression might be a potential predictor and monitor of cisplatin efficacy in advanced NSCLC patients.

AKR1C2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with AKR1C2

aldo-keto reductase family 1 member C2 (AKR1C2) Antikörper
aldo-keto reductase family 1, member C2 (Akr1c2) Antikörper

AKR1C-pseudo Antikörper
Akr1c21 Antikörper
BABP Antikörper
DD Antikörper
DD2 Antikörper
DDH2 Antikörper
HAKRD Antikörper
HBAB Antikörper
MCDR2 Antikörper
SRXY8 Antikörper

Bezeichner auf Proteinebene für AKR1C2

3-alpha-HSD3 , DD-2 , DD/BABP , aldo-keto reductase family 1 member C2 , chlordecone reductase homolog HAKRD , dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III , pseudo-chlordecone reductase , trans-1,2-dihydrobenzene-1,2-diol dehydrogenase , type II dihydrodiol dehydrogenase , 17-alpha-HSD , 17-alpha-hydroxysteroid dehydrogenase , 3(or 17)-alpha-hydroxysteroid dehydrogenase , 3-alpha-hydroxysteroid dehydrogenase , aldo-keto reductase family 1 member C21 , aldo-keto reductase family 1, member C21

GENE ID	SPEZIES
1646	Homo sapiens
291283	Rattus norvegicus

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Show all anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Antikörper with Pubmed References

Human Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with AKR1C2

Bezeichner auf Proteinebene für AKR1C2