anti-Nucleoporin 98kDa Antikörper

Protein Überblick

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described.

Alternative names and synonyms associated with Nucleoporin 98kDa (NUP98)

• Nucleoporin 98-96kD (Nup98-96) Antikörper
• nuclear pore complex protein Nup98-Nup96 (LOC408335) Antikörper
• nucleoporin 98 (NUP98) Antikörper
• nuclear pore complex protein Nup98-Nup96 (LOC587580) Antikörper
• nucleoporin 98kDa (NUP98) Antikörper
• Alle Gen-Bezeichnungen
• nucleoporin 98 (Nup98) Antikörper
• nucleoporin 98 (nup98) Antikörper
• nucleoporin 98 L homeolog (nup98.L) Antikörper

• 4732457F17 Antikörper
• ADIR2 Antikörper
• AI849286 Antikörper
• CG10198 Antikörper
• CG10201 Antikörper
• Alle Synonyme
• Dmel\\CG10198 Antikörper
• GB12688 Antikörper
• im:7151238 Antikörper
• l(3)95BCd Antikörper
• Nup-98 Antikörper
• NUP96 Antikörper
• Nup 96 Antikörper
• NUP98 Antikörper
• Nup 98 Antikörper
• nup98-96 Antikörper
• Nup98-Nup96 Antikörper
• Nup98/96 Antikörper
• nup145 Antikörper
• NUP196 Antikörper
• zgc:63593 Antikörper
• zgc:113968 Antikörper

Bezeichner auf Proteinebene für NUP98

CG10198-PA , CG10198-PC , CG10198-PD , Nup98 , Nup98-96-PA , Nup98-96-PC , Nup98-96-PD , nucleoporin 98 , nucleoporin 98-96 , nucleoporin98-96 , nucleoporin 98kD , nucleoporin 98kDa , nuclear pore complex protein Nup98-Nup96-like , nuclear pore complex protein Nup98-Nup96 , 98 kDa nucleoporin , nuclear pore complex protein Nup98 , nucleoporin Nup98 , GLFG-repeat containing nucleoporin , Nup98-Nup96