This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome)\; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008].
Holt, Zhang, Binia, Dixon, Vandiedonck, Cookson, Knight, Moffatt: "Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 4, pp. 1054-62.e1-2, (2011) (PubMed).
Aliase für SRY Proteine
sex determining region Y (SRY) Proteine sex determining region Y (Sry) Proteine sex determining region of Chr Y (Sry) Proteine SRXX1 Proteine SRXY1 Proteine SRY Proteine Sry1 Proteine Sry3BI Proteine SRYGENE Proteine TDF Proteine Tdf Proteine TDY Proteine Tdy Proteine