SPATA13 Proteine
(Spermatogenesis Associated 13 (SPATA13))
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
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custom-made
SPATA13
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
SPATA13
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Aliase für SPATA13 Proteine
spermatogenesis associated 13 (SPATA13) Proteinespermatogenesis associated 13 (Spata13) Proteine
ARHGEF29 Proteine
ASEF2 Proteine
C79050 Proteine
ESTM11 Proteine
mFLJ00298 Proteine
X83327 Proteine
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