SNCA Proteine
(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
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53 Treffer :
SNCA
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, in vitro, in vivo
Active
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>95% pure using SDS-PAGE analysis.
SDS, WB, in vitro, in vivo
Active
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, in vitro, in vivo
Active
custom-made
SNCA
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SNCA
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SNCA
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE
1 image
SNCA
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
1 image
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % pure
SDS
1 image
SNCA
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
SNCA
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
90 %
SDS, ELISA
1 image
3 Referenzen
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SNCA
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
SNCA
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
SNCA
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, PC, Imm
SNCA
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, PC, Imm
custom-made
SNCA
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aktuelle Publikationen für unsere SNCA Proteine
: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).
: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).
: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).
: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).
Aliase für SNCA Proteine
synuclein alpha L homeolog (snca.L) Proteinealpha-synuclein (LOC619283) Proteine
synuclein alpha (SNCA) Proteine
synuclein, alpha (Snca) Proteine
synuclein alpha (Snca) Proteine
alphaSYN Proteine
LOC619283 Proteine
MGC64356 Proteine
NACP Proteine
PARK1 Proteine
PARK4 Proteine
PD1 Proteine
snca Proteine
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- SNAP47 Proteine
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- SNAIL Proteine
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- SMU1 Proteine
- SMTNL1 Proteine
- SMS Proteine
- SMPX Proteine
- SMPDL3B Proteine
- SNCAIP Proteine
- SNCG Proteine
- SND1 Proteine
- SNF7 Proteine
- SNF8 Proteine
- SNIP1 Proteine
- SNRK Proteine
- SNRNP25 Proteine
- SNRNP27 Proteine
- SNRNP35 Proteine
- SNRNP40 Proteine
- SNRNP48 Proteine
- SNRNP70 Proteine
- SNRPB Proteine
- SNRPB2 Proteine
- SNRPC Proteine
- SNRPD1 Proteine
- SNRPD2 Proteine
- SNRPD3 Proteine
- SNRPE Proteine
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