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SNCA Proteine

(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

53 Treffer

custom-made SNCA Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Produktnummer ABIN3073847
 
SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5710386
 
SNCA Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
Produktnummer ABIN5713850
 
SNCA Spezies: Cynomolgus Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7479347
 
SNCA Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3011795
 
SNCA Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7586177
 
SNCA Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714638
 
SNCA Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714639
 
SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN6972940
 
SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant CA
Produktnummer ABIN1882770
 
Rockland 009-001-t45s SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95% WB
Produktnummer ABIN6700593
Rockland Original
MALS verified SNCA Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN7271629
 
MALS verified SNCA Spezies: Cynomolgus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN7273444
 
SNCA Spezies: Human Recombinant
Produktnummer ABIN1061348
 
SNCA Spezies: Human Recombinant
Produktnummer ABIN1061347
 
SNCA Spezies: Human Recombinant
Produktnummer ABIN1061346
 
SNCA Spezies: Human Recombinant
Produktnummer ABIN1061360
 
MALS verified SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 95,00 %
Produktnummer ABIN7316762
 
MALS verified SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 95,00 %
Produktnummer ABIN7316761
 
SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % Active
Produktnummer ABIN7488815
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • In vitro Assay (in vitro)
    • In vivo Studies (in vivo)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Cellular Assay (CA)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
    • Immunoprecipitation (IP)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Cynomolgus
    • Bonobo
    • Chimpanzee
    • Cow
    • Orang-Utan
    • Pig
    • Primate (Erythrocebus)
    • Red-chested mustached Tamarin (Saguinus labiatus)
    • Serinus canaria
    • Spider Monkey
    • Woolly Monkey
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • Bindungsspezifität
    • AA 1-140
    • full length
    • A53T
    • AA 23-140
    • AA 1-139
    • AA 1-143
    • AA 1-60
    • AA 31-140
    • AA 61-140
    • AA 96-140
    • E46K
    • R30P
    • Transcript Variant 2
    • Transcript Variant 3
    • active
    • partial
  • Konjugat
    • His tag
    • Unkonjugiert
    • GST tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • Biotin
    • Fc Tag
    • HiLyte Fluor 488
    • His tag,AVI tag,Biotin
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • MALS verified
    • custom-made
  • Hersteller
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Eurogentec
    • ITSI-Biosciences
    • OriGene
    • Signalway
    • Abbexa
    • Rockland

Aktuelle Publikationen für unsere SNCA Proteine

Xu, Li, Qin, Zhu, Zhou, Shi, Wang, Hu, Fan, Li: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).

Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).

Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

Aliase für SNCA Proteine

synuclein alpha L homeolog (snca.L) Proteine
alpha-synuclein (LOC619283) Proteine
synuclein alpha (SNCA) Proteine
synuclein, alpha (Snca) Proteine
synuclein alpha (Snca) Proteine
alphaSYN Proteine
LOC619283 Proteine
MGC64356 Proteine
NACP Proteine
PARK1 Proteine
PARK4 Proteine
PD1 Proteine
snca Proteine
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