This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008].
Merino, Singla: "Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin-Induced Apoptosis Mediated through the Akt-mTOR Pathway in Soleus Muscle." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6043064, (2018) (PubMed).
Aliase für SFRP2 Proteine
secreted frizzled-related protein 2 (sfrp2) Proteine secreted frizzled related protein 2 (SFRP2) Proteine secreted frizzled-related protein 2 S homeolog (sfrp2.S) Proteine secreted frizzled-related protein (sfrp2) Proteine sfrp2 (LOAG_01461) Proteine secreted frizzled-related protein 2 (Sfrp2) Proteine AI851596 Proteine frp-2 Proteine FRP-2 Proteine hm:zeh0225 Proteine sarp1 Proteine SARP1 Proteine sdf-5 Proteine SDF-5 Proteine Sdf5 Proteine sfrp-2 Proteine SFRP-2 Proteine SFRP2 Proteine sfrp2 Proteine zeh0225 Proteine zgc:153618 Proteine