Maus anti-Human IgG (Fd Region) Antikörper

Produktnummer ABIN952843

Kurzübersicht für Maus anti-Human IgG (Fd Region) Antikörper (ABIN952843)

Target: IgG

Klonalität: Monoklonal

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: HP6045

Isotyp: IgG1

Produktdetails

Bindungsspezifität: Fd Region

Reaktivität: Human

Wirt: Maus

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography.

Immunogen: Human IgG Fd

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.

Referenzen

Lebozec, Jandrot-Perrus, Avenard, Favre-Bulle, Billiald: "Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks." in: mAbs, Vol. 9, Issue 6, pp. 945-958, (2017) (PubMed).

Antigendetails

Target: IgG

Substanzklasse: Antibody

Hintergrund: The Fd region of Human Immunoglobulins is located at the N-terminal part of the heavy chain and is an essential component of the antigen-binding fragment Fab. Fd, like the light chain, contains a C-terminal constant (CH1) and N- terminal variable (VH) domain. The hypervariable regions in both the light chain and Fd determine the specificity of the Fab.Synonyms: Human Immunoglobulin G