Kaninchen anti-Human IgD (Chain delta) Antikörper

Produktnummer ABIN952831

Kurzübersicht für Kaninchen anti-Human IgD (Chain delta) Antikörper (ABIN952831)

Target: IgD

Klonalität: Polyklonal

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: Chain delta

Reaktivität: Human

Wirt: Kaninchen

Produktmerkmale: Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular Marginal Zone Lymphoma). Cytoplasmic staining is easily identified on paraffin tissue. Surface immunoglobulin is difficult to demonstrate on paraffin sections but can be demonstrated on frozen sections.

Aufreinigung: Purified

Immunogen: Purified IgD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Antigendetails

Target: IgD

Substanzklasse: Antibody

Hintergrund: Little is known about the normal function of IgD, and few clinical signs or symptoms are associated with its absence. Individuals with low or absent levels of IgD do not appear unusually predisposed to infections. In mice, IgD may substitute for some functions of IgM when IgM is absent. IgD is expressed on peripheral B cells and is used as a pan B cell marker.Synonyms: Human Immunoglobulin D