Maus anti-Human IgA Antikörper

Produktnummer ABIN7865652

Kurzübersicht für Maus anti-Human IgA Antikörper (ABIN7865652)

Target: IgA

Klonalität: Monoklonal

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: EBS-huA

Isotyp: IgG1 kappa

Produktdetails

Reaktivität: Human

Wirt: Maus

Verwendungszweck: anti-IgA (human) mouse monoclonal, EBS-huA, purified

Aufreinigung: affinity chromatography

Immunogen: human salivary proteins

Anwendungsinformationen

Applikationshinweise:

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Antigendetails

Target: IgA

Substanzklasse: Antibody

Hintergrund: EBS-huA recognizes the third constant domain (CH3) of the alpha chain of human IgA and reacts with both IgA1 and IgA2 isotypes and not with other types of immunoglobulins. IgA type antibodies are secreted by B-cells associated with mucosal epithelia and therefore indicate malignancy if found in lymphoid infiltrates at other locations. Detection of IgA antibodies to EBV in serum may indicate nasopharyngeal carcinoma. Rising IgA anti EBV levels are associated with progression of disease. Positive control: Human mucosal membranes, saliva.