Rekombinanter Kaninchen anti-Human IgD Antikörper

Produktnummer ABIN7828298

Kurzübersicht für Rekombinanter Kaninchen anti-Human IgD Antikörper (ABIN7828298)

Target: IgD

Antikörpertyp: Recombinant Antibody

Klonalität: Monoklonal

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Klon: A258

Isotyp: IgG, kappa

Produktdetails

Reaktivität: Human

Wirt: Kaninchen

Verwendungszweck: Recombinant Human IgD Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human Human IgD fragment

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:50,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: IgD

Substanzklasse: Antibody

Hintergrund: IGHD,IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 42 kDa

Observed MW: 75 kDa The actual band is not consistent with the expectation.

UniProt: P01880