Maus anti-Human IgD Antikörper (FITC)

Produktnummer ABIN7540455

Kurzübersicht für Maus anti-Human IgD Antikörper (FITC) (ABIN7540455)

Target: IgD

Klonalität: Monoklonal

Konjugat: FITC

Applikation: Flow Cytometry (FACS)

Klon: IA6-2

Isotyp: IgG2a kappa

Produktdetails

Reaktivität: Human

Wirt: Maus

Verwendungszweck: Anti-Hu IgD FITC

Spezifität: The mouse monoclonal antibody IA6-2 recognizes human immunoglobulin D.

Aufreinigung: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human IgD

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Antigendetails

Target: IgD

Substanzklasse: Antibody

Hintergrund:

Description: Immunoglobulin D (IgD) is expressed on the surface of naive mature B cells, thus later than IgM, and is coexpressed with it then. Triggered by antigen binding, it signals through the CD79 complex to activate the B cells. Expression of IgD is lost after the isotype switch. Soluble IgD is present in very small amounts in the serum. IgD can bind to basophils and mast cells to activate them in an IgE-independent way to participate in respiratory immune defense.

Other names: Immunoglobulin D