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Kaninchen anti-Human IgM Heavy Chain Antikörper

IHC (p) Monoclonal IGHM-2559R IgG kappa unconjugated
Produktnummer ABIN6654259
  • Target
    IgM Heavy Chain
    Reaktivität
    Human
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Monoklonal
    Applikation
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Purified
    Reinheit
    Protein A affinity chromatography
    Immunogen
    Recombinant heavy chain of human IgM was used as the immunogen for this recombinant IgM antibody.
    Klon
    IGHM-2559R
    Isotyp
    IgG kappa
  • Applikationshinweise
    The optimal dilution of the recombinant IgM antibody for each application should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store the recombinant IgM antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    IgM Heavy Chain
    Hintergrund
    Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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