Rekombinanter Kaninchen anti-Human IgM Heavy Chain (Heavy Chain) Antikörper

Produktnummer ABIN6654259

Kurzübersicht für Rekombinanter Kaninchen anti-Human IgM Heavy Chain (Heavy Chain) Antikörper (ABIN6654259)

Target: IgM Heavy Chain

Antikörpertyp: Recombinant Antibody

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: IGHM-2559R

Isotyp: IgG, kappa

Produktdetails

Bindungsspezifität: Heavy Chain

Reaktivität: Human

Wirt: Kaninchen

Verwendungszweck: Recombinant IgM Antibody

Aufreinigung: Protein A affinity chromatography

Immunogen: Recombinant heavy chain of human IgM was used as the immunogen for this recombinant IgM antibody.

Anwendungsinformationen

Applikationshinweise: The optimal dilution of the recombinant IgM antibody for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant IgM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: IgM Heavy Chain

Hintergrund: Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

UniProt: P01871