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Ziege anti-Human IgA (Free & Bound), (Secretory Component) Antikörper (Biotin)

WB, IF, IHC (fro), IP, EIA, ID, DB Polyclonal IgG Biotin
Produktnummer ABIN568605

Kurzübersicht für Ziege anti-Human IgA (Free & Bound), (Secretory Component) Antikörper (Biotin) (ABIN568605)

Target

IgA

Klonalität

  • 307
  • 72
Polyklonal

Konjugat

  • 106
  • 54
  • 51
  • 39
  • 24
  • 18
  • 9
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Biotin

Applikation

  • 194
  • 144
  • 130
  • 107
  • 106
  • 104
  • 60
  • 47
  • 46
  • 34
  • 27
  • 25
  • 23
  • 17
  • 16
  • 16
  • 14
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunodiffusion (ID), Dot Blot (DB)

Isotyp

IgG
  • Bindungsspezifität

    • 69
    • 61
    • 38
    • 17
    • 15
    • 12
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Free & Bound, Secretory Component

    Reaktivität

    • 188
    • 61
    • 45
    • 16
    • 15
    • 13
    • 13
    • 12
    • 12
    • 11
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human

    Wirt

    • 200
    • 109
    • 58
    • 17
    • 14
    • 6
    • 2
    Ziege

    Produktmerkmale

    Molar Ratio: Biotin/IgG aprox. 4.5

    Aufreinigung

    Hyperimmune antisera with strong precipitating activity are selected for Fractionation by Salt-Precipitation and purification of the IgG fraction by DEAE-Chromatography.

    Immunogen

    Purified free Human Secretory component isolated from pooled milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Rekonstitution

    Restore by adding 1.0 mL of sterile distilled water.

    Konzentration

    10.0 mg/mL

    Buffer

    PBS, pH 7.2 without preservatives and foreign proteins

    Konservierungsmittel

    Without preservative

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one week or (in aliquots) at -28 °C for longer.
  • Target

    IgA

    Substanzklasse

    Antibody

    Hintergrund

    Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM.Synonyms: Human Immunoglobulin A
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