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Maus anti-Human IgA (Free & Bound), (Secretory Component) Antikörper

WB, IF, IHC (fro), IP, EIA Monoclonal NI 194-4 (A89-039) IgG1 unconjugated
Produktnummer ABIN567760
  • Target Alle IgA Produkte
    IgA
    Bindungsspezifität
    • 105
    • 60
    • 38
    • 15
    • 14
    • 12
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Free & Bound, Secretory Component
    Reaktivität
    • 160
    • 58
    • 44
    • 16
    • 16
    • 14
    • 14
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 201
    • 98
    • 49
    • 17
    • 12
    • 6
    • 2
    Maus
    Klonalität
    • 308
    • 62
    Monoklonal
    Applikation
    • 182
    • 136
    • 130
    • 111
    • 100
    • 96
    • 55
    • 39
    • 39
    • 28
    • 28
    • 24
    • 23
    • 18
    • 17
    • 17
    • 17
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Ascites
    Immunogen
    Highly purified Secretory component isolated from Human milk.
    Klon
    NI 194-4 (A89-039)
    Isotyp
    IgG1
  • Applikationshinweise
    General Recommended Dilutions:
    Histochemical Use: from 1/50-1/200.
    ELISA: form 1/500 upwards.
    Western blot: from 1/1000 upwards.


    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore by adding 0.5 mL sterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2
    Konzentration
    1.0 mg/mL
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • Target
    IgA
    Abstract
    IgA Produkte
    Substanzklasse
    Antibody
    Hintergrund
    Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A
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