Kaninchen anti-Huhn IgY Antikörper (Biotin)

Produktnummer ABIN5662630

Kurzübersicht für Kaninchen anti-Huhn IgY Antikörper (Biotin) (ABIN5662630)

Target: IgY

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Isotyp: IgG

Produktdetails

Reaktivität: Huhn

Wirt: Kaninchen

Aufreinigung: Purified by Protein A.

Immunogen: Chicken IgY

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
IHC-P 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Aliquot to Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Referenzen

Ren, Wang, Ma, Yuan, Zhang, Yu, Hao: "Arnebia preventing the expression of Muc1 protein decrease results in anti-implantation in early pregnant mice." in: Contraception, Vol. 83, Issue 4, pp. 378-84, (2011) (PubMed).

Antigendetails

Target: IgY

Substanzklasse: Antibody

Hintergrund:

In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G (IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, these two types of immunoglobulin differ primarily in the heavy chains, which in IgY have a molecular mass of about 65,100 atomic mass units (amu), and are thus larger than in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, are somewhat smaller than the light chains in IgG. The molar mass of IgY thus amounts to about 167,000 amu. The steric flexibility of the IgY molecule is less than that of IgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well as to IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G, or to cellular Fc receptors. Furthermore, IgY does not activate the complement system. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie and L.W. Clem, after they were able to show differences between the immunoglobulins found in chicken eggs, and immunoglobulin G. Other synonymous names are Chicken IgG, Egg Yolk IgG, and 7S-IgG.

Synonyms: Egg yolk immunoglobulin, IgY.