Ziege anti-Human IgG Antikörper (PE) - Preadsorbed

Produktnummer ABIN376512

Kurzübersicht für Ziege anti-Human IgG Antikörper (PE) - Preadsorbed (ABIN376512)

Target: IgG

Fragment: F(ab')2 fragment

Klonalität: Polyklonal

Konjugat: PE

Applikation: Flow Cytometry (FACS), FLISA

Isotyp: IgG

Produktdetails

Reaktivität: Human

Wirt: Ziege

Verwendungszweck: Goat F(ab')2 Anti-Human IgG, Mouse ads-PE

Spezifität: Reacts with the heavy chain of human IgG

Produktmerkmale: Goat F(ab')2 Anti-Human IgG-PE antibody with minimal reactivity to mouse proteins for use in flow cytometry assays.

Aufreinigung:

Purified by affinity chromatography on human IgG covalently linked to agarose, cross-adsorbed against human IgM and IgA / mouse immunoglobulins and pooled sera for minimal reactivity

Preadsorption: Mouse pre-adsorbed

Immunogen: Human IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Pepsin digest of goat anti-human IgG (ABIN5707299) - Pooled antisera from goats hyperimmunized with human IgG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Referenzen

Brannan, He, Howell, Prugar, Zhu, Vu, Shulenin, Kailasan, Raina, Wong, Rahim, Banadyga, Tierney, Zhao, Li, Holtsberg, Dye, Qiu, Aman: "Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates." in: Nature communications, Vol. 10, Issue 1, pp. 105, (2019) (PubMed).

Gallery, Zhang, Bradley, Brauer, Cvet, Estevam, Danaee, Greenfield, Li, Manfredi, Loke, Rabino, Stringer, Williamson, Wyant, Yang, Zhu, Abu-Yousif, Veiby: "A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo." in: PLoS ONE, Vol. 13, Issue 1, pp. e0191046, (2018) (PubMed).

Kristian, Ota, Bubeck, Cho, Groff, Kubota, Destito, Martin, Laudenslager, Koriazova, Tahara, Kanda: "Generation and Improvement of Effector Function of a Novel Broadly Reactive and Protective Monoclonal Antibody against Pneumococcal Surface Protein A of Streptococcus pneumoniae." in: PLoS ONE, Vol. 11, Issue 5, pp. e0154616, (2017) (PubMed).

Schubert, Bode, Kenefeck, Hou, Wing, Kennedy, Bulashevska, Petersen, Schäffer, Grüning, Unger, Frede, Baumann, Witte, Schmidt, Dueckers, Niehues, Seneviratne, Kanariou, Speckmann, Ehl, Rensing-Ehl et al.: "Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. ..." in: Nature medicine, Vol. 20, Issue 12, pp. 1410-1416, (2015) (PubMed).

Antigendetails

Target: IgG

Substanzklasse: Antibody

Hintergrund: Optional[Description]: Goat F(ab')2 Anti-Human IgG, Mouse ads-PE