Kurzübersicht für Maus anti-Maus IgMb Antikörper (Biotin) (ABIN2689713)
Target
Klonalität
Konjugat
Applikation
Klon
Isotyp
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Reaktivität
- Maus
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Wirt
- Maus
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Produktmerkmale
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The AF6-78 antibody reacts specifically with mouse IgM of Igh-C[b] and related haplotypes (e.g., C57BL/6, C57BL/10, SJL, AKR, NZB). It does not react with IgM of Igh-C[a] or related haplotypes (e.g., BALB/c, C58, CBA, C3H/Bi, C3H/He, DBA/1, DBA/2, PL, RIII). Cross-reaction with IgM of Igh-C[e] haplotype (e.g., A/J) has been observed. AF6-78 antibody does not react with free μ heavy chain in vitro or in the cytoplasm of pre-B lymphocytes, which lack Ig light chain. It has not been shown to stimulate B-cell proliferation.
BD Pharmingen™ Biotin Mouse Anti-Mouse IgM[b] - Biotin - Clone AF6-78 - Isotype Mouse IgG1, κ - Reactivity Ms - 0.5 mg -
Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogen
- C57BL/10 mouse splenocytes
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Allotypic specificities of murine IgD and IgM recognized by monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 132, Issue 2, pp. 787-95, (1984) (PubMed).
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- IgMb
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Andere Bezeichnung
- IgM[b]
Target
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