Maus anti-Human IgG4 (full length) Antikörper

Produktnummer ABIN2127702

Kurzübersicht für Maus anti-Human IgG4 (full length) Antikörper (ABIN2127702)

Target: IgG4

Klonalität: Monoklonal

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Isotyp: IgG

Produktdetails

Bindungsspezifität: full length

Reaktivität: Human

Wirt: Maus

Produktmerkmale: The antibody is a mouse monoclonal antibody raised against IgG4. It has been selected for its ability to recognize IgG4 in immunohistochemical staining and western blotting.

Aufreinigung: Affinity Chromatography

Immunogen: Full Length IgG4 of Human Plasma

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 500 μg/mL

Buffer: PBS, pH 7.4, containing 0.02 % NaN3, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Store at 4 °C for frequent use. Stored at -20 °C to -80 °C in a manual defrost freezer for one year without detectable loss of activity.

Haltbarkeit: 12 months

Antigendetails

Target: IgG4

Andere Bezeichnung: Immunoglobulin G4 (IgG4)

Substanzklasse: Antibody

Hintergrund: There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections.