The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008].
Kim, Denli, Wright, Baul, Clemenson, Morcos, Zhao, Schafer, Gage, Kagalwala: "REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 44, pp. 14872-84, (2015) (PubMed).
Aliase für SCG2 Proteine
secretogranin II L homeolog (scg2.L) Proteine secretogranin II (chromogranin C), b (scg2b) Proteine secretogranin II (scg2) Proteine secretogranin II (SCG2) Proteine Secretogranin-2 (scg2) Proteine secretogranin II (Scg2) Proteine Chcg Proteine CHGC Proteine Chgc Proteine DKFZp459O193 Proteine EM66 Proteine LOC397939 Proteine MGC84703 Proteine MGC145924 Proteine scg2 Proteine SCG2 Proteine SCGG2 Proteine SgII Proteine SN Proteine wu:fj34e01 Proteine zgc:153925 Proteine