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RVFV G Protein (His tag)

Dieses Recombinant RVFV G-Protein wird in Baculovirus infected Insect Cells produziert.
Produktnummer ABIN7195956

Kurzübersicht für RVFV G Protein (His tag) (ABIN7195956)

Target

RVFV G (Rift Valley Fever Virus Glycoprotein (RVFV G))

Protein-Typ

Recombinant

Spezies

Rift Valley Fever Virus (RVFV)

Quelle

Baculovirus infected Insect Cells

Reinheit

> 90 as determined by SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses RVFV G Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Rift Valley fever virus (RVFV) (strain MP12) glycoprotein / G2 Protein (His Tag)

    Sequenz

    Cys691-Ser1139

    Produktmerkmale

    A DNA sequence encoding the Rift Valley fever virus (RVFV) (strain MP12) Gc (ABD38821.1) (Cys691-Ser1139) was expressed with a polyhistidine tag at the N-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg protein as determined by the LAL method.
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    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem Rabbit
    Konjugat
    Origin Discosoma
    Preis ab 455,00 €
    Expressionssystem Guinea Pig
    Konjugat
    Origin Rabbit
    Preis ab 455,00 €
    Expressionssystem Rabbit
    Konjugat
    Origin Cow, Human, Mouse, Pig, Rabbit, Rat
    Preis ab 129,85 €
    Expressionssystem Rabbit
    Konjugat
    Origin Cow, Human, Mouse, Pig, Rat
    Preis ab 675,84 €
    Expressionssystem Rabbit
    Konjugat
    Origin Coral
    Preis ab 463,75 €
    Expressionssystem Rabbit
    Konjugat
    Origin Human, Monkey, Mouse, Pig, Rat, Sheep
    Preis ab 384,62 €
    Expressionssystem Rabbit
    Konjugat
    Origin Horse, Human, Mouse, Rabbit, Rat
    Preis ab 384,62 €
    Expressionssystem Rabbit
    Konjugat
    Origin Human, Mouse, Rat
    Preis ab 384,62 €
    Expressionssystem Goat
    Konjugat
    Origin Dog, Human, Monkey, Mouse, Rat
    Preis ab 633,60 €
    Expressionssystem Rabbit
    Konjugat
    Origin Human
    Preis ab 659,23 €

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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile 20 mM Tris,150 mM NaCl, pH 8.0,10 % glycerol Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    RVFV G (Rift Valley Fever Virus Glycoprotein (RVFV G))

    Andere Bezeichnung

    RVFV-G

    Substanzklasse

    Viral Protein

    Hintergrund

    Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. HRSV G protein is a type II glycoprotein of 289-299 amino acids (depending on the virus strain) with a signal/anchor hydrophobic domain and is extensively modified by the addition of both N-and O-linked oligosaccharides to achieve the mature form of 8-9 kDa. The C-terminal ectodomain of the G protein has a central region and four cysteines which are conserved in all HRSV isolates and have been proposed as the putative receptor binding site. The G protein mediates attachment of the virus to the host cell membrane by interacting with heparan sulfate, initiating the infection. As similar to mucins in amino acid compositions, the RSV G protein can interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, and thus modulates the immune response and facilitate infection. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors. Unlike the other paramyxovirus attachment proteins, HRSV-G lacks both neuraminidase and hemagglutinating activities.

    Molekulargewicht

    50.1kDa.
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