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anti-Human TYRO3 Antikörper:
anti-Rat (Rattus) TYRO3 Antikörper:
anti-Mouse (Murine) TYRO3 Antikörper:
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Mouse (Murine) Monoclonal TYRO3 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4900191
Fujimori, Grabiec, Kaur, Bell, Fujino, Cook, Svedberg, MacDonald, Maciewicz, Singh, Hussell: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. in Mucosal immunology 2015
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Human Monoclonal TYRO3 Primary Antibody für IF, ELISA - ABIN967221
Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: A novel putative tyrosine kinase receptor with oncogenic potential. in Oncogene 1991
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Human Monoclonal TYRO3 Primary Antibody für FACS - ABIN4897539
Gould, Baxi, Schroeder, Peng, Leadley, Peterson, Perrin: Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses. in Journal of thrombosis and haemostasis : JTH 2005
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Human Polyclonal TYRO3 Primary Antibody für ELISA, IP - ABIN2747776
Uehara, Shacter: Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells. in Journal of immunology (Baltimore, Md. : 1950) 2008
Human Monoclonal TYRO3 Primary Antibody für ELISA, WB - ABIN969449
Lan, Wu, Li, Wu, Lu, Xu, Dai: Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway. in Blood 2000
Human Monoclonal TYRO3 Primary Antibody für ELISA, WB - ABIN967222
Heiring, Dahlbäck, Muller: Ligand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase family. in The Journal of biological chemistry 2004
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Human Monoclonal TYRO3 Primary Antibody für ELISA, WB - ABIN967223
Hafizi, Gustafsson, Stenhoff, Dahlbäck: The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases. in The international journal of biochemistry & cell biology 2005
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Mouse (Murine) Monoclonal TYRO3 Primary Antibody für FACS - ABIN4897330
Taichman, Patel, Bedenis, Wang, Weidner, Schumann, Yumoto, Berry, Shiozawa, Pienta: GAS6 receptor status is associated with dormancy and bone metastatic tumor formation. in PLoS ONE 2013
Human Polyclonal TYRO3 Primary Antibody für FACS, ICC - ABIN440474
Chan, Carrera Silva, De Kouchkovsky, Joannas, Hao, Hu, Huntsman, Eng, Licona-Limón, Weinstein, Herbert, Craft, Flavell, Repetto, Correale, Burchard, Torgerson, Ghosh, Rothlin: The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity. in Science (New York, N.Y.) 2016
Phosphatidylserine mediated hyperactivation of TYRO3.TYRO3 promotes epithelial cell efferocytosis in a tyrosine kinase (zeige TXK Antikörper)-dependent manner.TYRO3 role in AKT (zeige AKT1 Antikörper)-dependent drug resistance.
Taken together, our data indicate that elevated plasma Gas6 (zeige GAS6 Antikörper) levels is associated with the severity of disease during HTNV infection in humans, suggesting that Gas6 (zeige GAS6 Antikörper) may play an important role by binding with Tyro3 on monocytes.
Study identified the Gas6 (zeige GAS6 Antikörper)/TAM (zeige CCNA1 Antikörper) receptor pathway with Tyro3 and Mer (zeige MERTK Antikörper) as novel targets in colorectal cancer.
These results show that TYRO3, AXL (zeige AXL Antikörper) and GAS6 (zeige GAS6 Antikörper) are expressed at higher levels in LMS and expression of its ligands correlates to a worse PFS in LMS patients.
Patients with macroalbuminuria diabetes had higher circulating levels of sMer and more urinary soluble Tyro3 and sMer than normoalbuminuric diabetics. Increased clearance of sTyro3 and sMer was associated with loss of tubular Tyro3 and Mer (zeige MERTK Antikörper) expression in diabetic nephropathy tissue. During in vitro diabetes, human kidney cells had down-regulation of Tyro3 and Mer (zeige MERTK Antikörper) mRNA and increased shedding of sTyro3 and sMer.
TYRO3 is overexpressed in the early stage of colon cancer development and aberrant expression of TYRO3 promotes tumorigenesis and induces EMT (zeige ITK Antikörper) through the regulation of SNAI1 (zeige SNAI1 Antikörper).
In this paper, we review the biology of the Gas6 (zeige GAS6 Antikörper)/Tyro3, Axl (zeige AXL Antikörper), and MerTK (zeige MERTK Antikörper)(collectively named TAM (zeige CCNA1 Antikörper) system)and the current evidence supporting its potential role in the pathogenesis of multiple sclerosis .
these data suggest that Tyro3 contributes significantly to tumor growth, aggressiveness and liver dysfunction
Tyro3 gene dosage modulates Mertk (zeige MERTK Antikörper)-associated retinal degeneration, provide strong evidence for a direct role for TYRO3 in RPE (zeige RPE Antikörper) phagocytosis, and suggest that an eQTL (zeige EQTN Antikörper) can modify a recessive Inherited photoreceptor degenerations.
The mRNA expression levels of Tyro-3, Axl (zeige AXL Antikörper) were decreased in pSS (zeige CDSN Antikörper) patients. When considering the plasma level, increased levels of soluble Mer (zeige MERTK Antikörper) was observed with statistically significant difference.
Disinhibiation of Gas6 (zeige GAS6 Antikörper) binding to Tyro3 due to PGRN (zeige GRN Antikörper) reduction results in activation of PKCalpha (zeige PKCa Antikörper) via PLCgamma, inducing tau phosphorylation at Ser203, mislocalization of tau to dendritic spines, and spine loss.
shows that Tyro3 has prosurvival roles in the appetite regulatory circuitry and could also provide useful insights towards the development of interventions targeting detrimental weight loss
The findings of this study indicated the critical importance of Tyro3 in potentiating central nervous system myelination
This study mapped the autophosphorylation sites of murine Tyro3 to tyrosine 723 and 756, with K540 being required for its kinase activity.
Axl (zeige AXL Antikörper), Mertk (zeige MERTK Antikörper) and Tyro3 receptors are not required for Zika virus entry and infection.
genetic ablation of a receptor tyrosine kinase (zeige ERBB3 Antikörper) encoded byTyro3in mice or the functional neutralization of its ortholog in human dendritic cells resulted in enhanced type 2 immunity.
These results suggest that TAM (zeige CCNA1 Antikörper) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.
Optimal TAM (zeige CCNA1 Antikörper) signaling requires coincident TAM (zeige CCNA1 Antikörper) ligand engagement of both its receptor and the phospholipid phosphatidylserine regulating TAM (zeige CCNA1 Antikörper) receptor tyrosine kinases Tyro3, Axl (zeige AXL Antikörper), and Mer (zeige ERH Antikörper) and their ligands Gas6 (zeige GAS6 Antikörper) and Protein S.
These findings indicate that Tyro3 is a critical signal for synovial hyperplasia, osteoclast differentiation and bone erosion during arthritis.
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
TYRO3 protein tyrosine kinase
, Tyrosine-protein kinase receptor TYRO3
, tyrosine-protein kinase receptor TYRO3
, developmental receptor tyrosine kinase
, tyrosine-protein kinase DTK
, tyrosine-protein kinase receptor TYRO3-like
, tyrosine-protein kinase RSE
, tyrosine-protein kinase SKY
, tyrosine-protein kinase TIF
, tyrosine-protein kinase byk
, Bruton agammaglobulinemia tyrosine kinase
, TYRO3 protein tyrosine kinase 3
, Axl-related receptor tyrosine kinase
, protein-tyrosine kinase
, retina-expressed kinase
, Xenopus kinase of Sky family
, tyrosine kinase