Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human ARPC1B Antikörper:
anti-Rat (Rattus) ARPC1B Antikörper:
anti-Mouse (Murine) ARPC1B Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal ARPC1B Primary Antibody für ELISA, WB - ABIN268667
Moghe, Jiang, Miura, Cerny, Tsai, Furukawa: The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. in Biology open 2012
Show all 3 Pubmed References
Human Polyclonal ARPC1B Primary Antibody für IHC, IHC (p) - ABIN4278119
Abella, Galloni, Pernier, Barry, Kjær, Carlier, Way: Isoform diversity in the Arp2/3 complex determines actin filament dynamics. in Nature cell biology 2015
Show all 2 Pubmed References
Results indicate activation-induced cytidine deaminase (AICDA (zeige AICDA Antikörper)) as a driver of epigenetic heterogeneity in B-cell lymphomas with potential significance for other tumors with aberrant expression of cytidine deaminases.
A homozygous frameshift mutation in ARPC1B (p.Val91Trpfs*30) was identified in a child with microthrombocytopenia, eosinophilia and inflammatory disease. Platelet lysates contained no ARPC1B protein and reduced Arp2 (zeige ACTR2 Antikörper)/3 complex. Missense ARPC1B mutations were identified in an unrelated patient with similar symptoms and ARPC1B deficiency. ARPC1B-deficient platelets are microthrombocytes with abnormal spreading behavior.
The binding and catalytic behavior of purified AID was tested on DNA/RNA hybrid substrates bearing either random sequences or GC-rich (zeige RELB Antikörper) sequences simulating Ig S regions. AID exhibited a higher affinity for binding DNA/RNA hybrid substrates made of S region sequences, than any other DNA substrates. In the absence of any other cellular processes or factors, AID itself favors binding and mutating S-region DNA/RNA hybrids.
A homozygous 2 bp deletion, n.c.G623DEL-TC (p.V208VfsX20), in Arp2 (zeige ACTR2 Antikörper)/3 complex component ARPC1B that causes a frame shift resulting in premature termination was found in 2 brothers with hematopoietic and immunologic symptoms reminiscent of Wiskott-Aldrich syndrome. Wild-type ARPC1B but not mutant was able to rescue a deficiency in a zebrafish model. ARPC1B expression is restricted to hematopoietic cells.
This study identified two low-frequency nonsynonymous variants at FKBPL (zeige FKBPL Antikörper) (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and ARPC1B (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk.
silencing of AID in human bone marrow cells skews differentiation toward myelomonocytic lineage. However, in contrast to Tet2 (zeige TET2 Antikörper) loss, Aid loss does not contribute to enhanced HSC (zeige FUT1 Antikörper) self-renewal or cooperate with Flt3 (zeige FLT3 Antikörper)-ITD to induce myeloid transformation. Genome-wide transcription and differential methylation analysis uncover the critical role of Aid as a key epigenetic regulator
These findings indicated that TNF-alpha (zeige TNF Antikörper)-induced AID expression is involved with class switch recombination in cancer.
Finnish founder allele causing HIGM2 (zeige AICDA Antikörper) identified.
low-expression of ARPC1B is significantly associated with LNM and advanced tumor staging whereas high expression of Cav-1 (zeige CAV1 Antikörper) can be a prognostic indicator for poor prognosis in OSCC patients.
this study reports a case of growth hormone (zeige GH1 Antikörper) deficiency with an autosomal recessive Hyper-immunoglobulin M syndrome by phenotype and genotype, with a novel mutation in AICDA (zeige AICDA Antikörper) that has not been reported formerly
The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
, integrated into Burkitt's lymphoma cell line Ramos
, single-stranded DNA cytosine deaminase
, ARP2/3 protein complex subunit p41
, actin-related protein 2/3 complex subunit 1B
, arp2/3 complex 41 kDa subunit
, Actin-related protein complex 1b
, actin related protein 2/3 complex subunit 1B
, ARP2/3 complex 41 kDa subunit
, actin related protein 2/3 complex, subunit 1A, 41kDa
, actin related protein 2/3 complex, subunit 1B, 41kDa
, actin-related protein 2/3 complex subunit 1B-like