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RNF111 Produkte

(Ring Finger Protein 111 (RNF111))
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].

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Ausgewählte RNF111 Kategorien

RNF111 Antikörper

High quality antibodies with extensive validation data.

RNF111 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RNF111 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, RNAi
Validierungen
  • (9)
  • (5)
Kat. Nr. ABIN527194
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN527193
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6257485
Menge 100 μL
Datenblatt Datenblatt

Empfohlene RNF111 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1318194
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3095070
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136968
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RNF111 Produkten

Mizutani, Koinuma, Seimiya, Miyazono: "The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma." in: Oncogene, Vol. 35, Issue 27, pp. 3514-23, (2016) (PubMed).

van Cuijk, van Belle, Turkyilmaz, Poulsen, Janssens, Theil, Sabatella, Lans, Mailand, Houtsmuller, Vermeulen, Marteijn: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." in: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).

Zhou, Drabsch, Dekker, de Vinuesa, Li, Hawinkels, Sheppard, Goumans, Luwor, de Vries, Mesker, Tollenaar, Devilee, Lu, Zhu, Zhang, Dijke: "Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling." in: Nature communications, Vol. 5, pp. 3388, (2014) (PubMed).

Sun, Liu, Hunter: "Multiple Arkadia/RNF111 structures coordinate its Polycomb body association and transcriptional control." in: Molecular and cellular biology, Vol. 34, Issue 16, pp. 2981-95, (2014) (PubMed).

Ma, Chen, Zhang, Yang, Wang, Yu: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." in: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).

Erker, Neyret-Kahn, Seeler, Dejean, Atfi, Levy: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." in: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).

Poulsen, Hansen, Wagner, van Cuijk, van Belle, Streicher, Wikström, Choudhary, Houtsmuller, Marteijn, Bekker-Jensen, Mailand: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).

Javelaud, van Kempen, Alexaki, Le Scolan, Luo, Mauviel: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." in: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).

Koinuma, Shinozaki, Nagano, Ikushima, Horiguchi, Goto, Chano, Saitoh, Imamura, Miyazono, Miyazawa: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).

Nagano, Koinuma, Miyazawa, Miyazono: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." in: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).

Synonyme und alternative Namen zu RNF111

ring finger protein 111 (RNF111), ring finger 111 (Rnf111), ring finger protein 111 (Rnf111), ring finger protein 111 (rnf111-b), ring finger protein 111 (rnf111), ARK, ark, Arkadia, MGC81253, MGC146379, RNF111, rnf111

Bezeichner auf Proteinebene für RNF111

  • Arkadia
  • E3 ubiquitin-protein ligase Arkadia
  • RING finger protein 111
  • ring finger 111
  • arkadia
  • ring finger protein 111
  • E3 ubiquitin-protein ligase arkadia-B
  • RING finger protein 111-B
  • e3 ubiquitin-protein ligase Arkadia-like
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