anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Antikörper

Bezeichnung:: anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Antikörper (PCMT1)

Auf www.antikoerper-online.de finden Sie aktuell 81 Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Proteine (14) und Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 109 Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Produkte verfügbar.

Synonyme:: C79501, etID309741.20, fj13d06, PCM, PCMT, pimt, wu:fj13d06

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	PCMT1	5110	P22061
	PCMT1	18537
	PCMT1	25604	P22062
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human Antikörper:

anti-Mouse (Murine) Antikörper:

anti-Rat (Rattus) Antikörper:

Alle verfügbaren anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Verknüpfte Pathways mit anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Antikörper

Ribonucleoprotein Complex Subunit Organization

Weitere Produktkategorien zu Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Antikörper

Am meisten referenzierte anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Antikörper

Human Polyclonal PCMT1 Primary Antibody für ICC, IF - ABIN4344090 : Forsström, Axnäs, Stengele, Bühler, Albert, Richmond, Hu, Nilsson, Hudson, Rockberg, Uhlen: Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays. in Molecular & cellular proteomics : MCP 2014 (PubMed)

Weitere Antikörper gegen Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase Interaktionspartner

Human Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Interaktionspartner

decrease of PCMT1 significantly increased the proportion of D-Asp (zeige ASIP Antikörper) residues in PHB1 (zeige PHB Antikörper) and had significant and fatal impacts on morphology and functions of the mitochondria, such as ATP production and the mitochondrial fusion-fission system
PIMT heterozygosity for R36C, G175R, R17H, or R17S would be detrimental to successful aging, whereas homozygosity (should it ever occur) would produce devastating neuropathology
Strong PIMT expression was a predictive marker of poor prognosis for surgically resected lung adenocarcinoma.
The data of this study indicated that DA-associated PIMT downregulation is an important event contributing to neuronal cell death
ERK2 (zeige MAPK1 Antikörper)-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP (zeige TGS1 Antikörper) at Ser298 augments hepatic gluconeogenesis.
Overexpression of PCMT1 attentuates Mst1 (zeige MST1 Antikörper) kinase activation and its apoptotic effects in response to hypoxia-induced injury in cardiomyocytes.
Data indicate that human PROTEIN ISOASPARTYL METHYLTRANSFERASE (PIMT) can initiate isoAsp conversion to Asp (zeige ASIP Antikörper), and is able to restore Arabidopsis PRH75 (zeige DDX46 Antikörper)'s complex biochemical activity provided isoAsp formation has not led to conformational alterations.
Data show six differentially expressed proteins were identified as HSP70 (zeige HSP70 Antikörper), PPIA (zeige PPIA Antikörper) and alpha-Enolase (up-regulated) S100-A9, PIMT and beta-5 tubulin (zeige TUBB Antikörper) (down-regulated), most of which had been shown to play a potential role in the pathogenesis of atherosclerosis.
The results implied that maternal polymorphisms in PCMT1 might be a potential genetic risk factor for isolated anencephaly in the Chinese population of Lvliang.
Study provides new insight into the molecular mechanisms by which PIMT suppresses the p53 (zeige TP53 Antikörper) activity through carboxyl methylation, and suggests a therapeutic target for cancers.

Mouse (Murine) Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Interaktionspartner

Loss of normal CKB (zeige CHKB Antikörper) structure and function contributes to the mechanisms by which isoaspartate accumulation leads to central nervous system dysfunction in the PIMT-Knockout mouse.
PIMT levels may significantly influence the course of age-related central nervous system dysfunction.
ERK2 (zeige MAPK1 Antikörper)-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP (zeige TGS1 Antikörper) at Ser298 augments hepatic gluconeogenesis.
PIMT knockout mice have perturbations in glutamate (zeige GRIN1 Antikörper) metabolism in the brain and die prematurely of epileptic seizures.
synuclein is not a major target of PIMT in vivo
Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of PCMT1 knockout mice
Recombinant adeno (zeige ADORA2A Antikörper)-PIMT improved the symptoms of PIMT-deficient mice in vivo, but only partially repaired IsoAsp in damaged proteins.
An accumulation of isoaspartyl residues in cells of mice lacking the isoaspartyl repair enzyme PCMT alters the effector function of T lymphocytes leading to autoantibody production.
Pcmt1-/- mice have altered regulation of the insulin (zeige INS Antikörper) pathway, possibly as a compensatory response to altered glucose uptake or metabolism or as an adaptive response to a general accumulation of isoaspartyl protein damage in the brain and other tissues.
Protein L-isoaspartyl methyltransferase (PIMT) catalyzes in vivo racemization of Asp (zeige C3 Antikörper)-25 in mammalian histone H2B, suggesting that PIMT functions in the repair, rather than the metabolic turnover, of isoaspartyl proteins in vivo.

Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1)

protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) Antikörper
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 (Pcmt1) Antikörper
protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog (pcmt1.L) Antikörper
protein-L-isoaspartate(D-aspartate)O-methyltransferase (pcmt1) Antikörper
protein-L-isoaspartate (D-aspartate) O-methyltransferase (Pcmt1) Antikörper
protein-L-isoaspartate (D-aspartate) O-methyltransferase (pcmt) Antikörper

C79501 Antikörper
etID309741.20 Antikörper
fj13d06 Antikörper
PCM Antikörper
PCMT Antikörper
pimt Antikörper
wu:fj13d06 Antikörper

Bezeichner auf Proteinebene für PCMT1

L-isoaspartyl protein carboxyl methyltransferase , protein L-isoaspartyl/D-aspartyl methyltransferase , protein-L-isoaspartate(D-aspartate) O-methyltransferase , protein-beta-aspartate methyltransferase , protein carboxyl methyltransferase , PIMT , protein carboxyl-o-methyltransferase , protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 , Protein L-isoaspartyl/D-aspartyl methyltransferase , Protein-beta-aspartate methyltransferase , l-isoaspartyl protein carboxyl methyltransferase

GENE ID	SPEZIES
5110	Homo sapiens
18537	Mus musculus
25604	Rattus norvegicus
428607	Gallus gallus
476242	Canis lupus familiaris
100502562	Sus scrofa
613854	Bos taurus
495685	Xenopus laevis
100172708	Pongo abelii
380580	Xenopus laevis
100731541	Cavia porcellus
30751	Danio rerio

Ausgewählte Anbieter für anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Antikörper

Haben Sie etwas anderes gesucht?

Telefon:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antikoerper-online.de

Show all anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Antikörper with Pubmed References

Human Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Interaktionspartner

Mouse (Murine) Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1)

Bezeichner auf Proteinebene für PCMT1