Ring Finger Protein 8 Proteine
(Ring Finger Protein 8 (RNF8))
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
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RNF8
Spezies: Human
Wirt: Wheat germ
Recombinant
ELISA, WB, AP, AA
1 image
2 Referenzen
custom-made
RNF8
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
RNF8
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
RNF8
Spezies: Zebrafisch (Danio rerio)
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aktuelle Publikationen für unsere Ring Finger Protein 8 Proteine
: "Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 3, pp. 1029-34, (2013) (PubMed).: "Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1." in: Nature, Vol. 466, Issue 7309, pp. 941-6, (2010) (PubMed).
Aliase für Ring Finger Protein 8 Proteine
ring finger protein 8 (RNF8) Proteinering finger protein 8 (Rnf8) Proteine
ring finger protein 8, E3 ubiquitin protein ligase S homeolog (rnf8.S) Proteine
ring finger protein 8, E3 ubiquitin protein ligase L homeolog (rnf8.L) Proteine
ring finger protein 8, E3 ubiquitin protein ligase (rnf8) Proteine
3830404E21Rik Proteine
AIP37 Proteine
fc66f09 Proteine
hRNF8 Proteine
RNF8 Proteine
rnf8 Proteine
wu:fc66f09 Proteine
zgc:55936 Proteine
zgc:77313 Proteine
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