RFX5 Produkte
(Regulatory Factor X 5 (RFX5))
Kategorien
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte RFX5 Kategorien
RFX5 Antikörper
High quality antibodies with extensive validation data.
RFX5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RFX5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, GS
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN106544
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN948403
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7150384
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RFX5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6207337
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RFX5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317888
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317890
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN3087081
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RFX5 Produkten
: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." in: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).: "The transcription factor RFX5 is a transcriptional activator of the TPP1 gene in hepatocellular carcinoma." in: Oncology reports, Vol. 37, Issue 1, pp. 289-296, (2017) (PubMed).
: "Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148753, (2016) (PubMed).
: "In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport." in: Infection and immunity, Vol. 83, Issue 8, pp. 3268-80, (2015) (PubMed).
: "PML promotes MHC class II gene expression by stabilizing the class II transactivator." in: The Journal of cell biology, Vol. 199, Issue 1, pp. 49-63, (2012) (PubMed).
: "HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells." in: Journal of molecular and cellular cardiology, Vol. 46, Issue 3, pp. 292-9, (2009) (PubMed).
: "Identifying catalytic residues in CPAF, a Chlamydia-secreted protease." in: Archives of biochemistry and biophysics, Vol. 485, Issue 1, pp. 16-23, (2009) (PubMed).
: "Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9260-70, (2006) (PubMed).
Synonyme und alternative Namen zu RFX5
regulatory factor X5 (RFX5), regulatory factor X, 5 (influences HLA class II expression) (Rfx5), regulatory factor X5 (Rfx5)Bezeichner auf Proteinebene für RFX5
- DNA-binding protein RFX5
- regulatory factor X 5
- DNA-binding protein Rfx5
- regulatory factor X, 5
- regulator factor X 5
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