We are preparing the requested document. Please wait, this may take a while...!
There was a problem generating the requested document, please try again.
SP100 Antigen Profile
Beschreibung des Gens
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene\; one of which encodes a high-mobility group protein.
Alternative names and synonyms associated with SP100