anti-GRIN2B (GRIN2B) Antikörper

Bezeichnung:
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B Antikörper (GRIN2B)
Auf www.antikoerper-online.de finden Sie aktuell 391 Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GRIN2B Kits (22) und GRIN2B Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 432 GRIN2B Produkte verfügbar.
Synonyme:
AW490526, GluN2B, hNR3, MRD6, Nmdar2b, nr2b

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Am meisten referenzierte anti-GRIN2B Antikörper

  1. Human Monoclonal GRIN2B Primary Antibody für BI, IF - ABIN967955 : Fallon, Moreau, Croft, Labib, Gu, Fon: Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 5 Referenzen für 967955

  2. Human Polyclonal GRIN2B Primary Antibody für IF - ABIN401598 : Liu, Murray, Jones: Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Zeige alle 4 Referenzen für 401598

  3. Human Polyclonal GRIN2B Primary Antibody für IF - ABIN401622 : Browning, Wang, Lanker, Jobe: Electroshock- and pentylenetetrazol-induced seizures in genetically epilepsy-prone rats (GEPRs): differences in threshold and pattern. in Epilepsy research 1990 (PubMed)
    Zeige alle 3 Referenzen für 401622

  4. Human Polyclonal GRIN2B Primary Antibody für ELISA, WB - ABIN251562 : Arning, Kraus, Valentin, Saft, Andrich, Epplen: NR2A and NR2B receptor gene variations modify age at onset in Huntington disease. in Neurogenetics 2005 (PubMed)
    Zeige alle 2 Referenzen für 251562

  5. Rat (Rattus) GRIN2B Primary Antibody für ELISA, WB - ABIN1742592 : Strack, McNeill, Colbran: Mechanism and regulation of calcium/calmodulin-dependent protein kinase II targeting to the NR2B subunit of the N-methyl-D-aspartate receptor. in The Journal of biological chemistry 2000 (PubMed)
    Zeige alle 2 Referenzen für 1742592

  6. Human Polyclonal GRIN2B Primary Antibody für IF (p), IHC (p) - ABIN744368 : Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014 (PubMed)
    Zeige alle 2 Referenzen für 744368

  7. Human Monoclonal GRIN2B Primary Antibody für ICC, IHC - ABIN261572 : Ramberger, Peschl, Schanda, Irschick, Höftberger, Deisenhammer, Rostásy, Berger, Dalmau, Reindl: Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay. in PLoS ONE 2015 (PubMed)

  8. Human Polyclonal GRIN2B Primary Antibody für ELISA, WB - ABIN1533143 : Mandich, Schito, Bellone, Antonacci, Finelli, Rocchi, Ajmar: Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12. in Genomics 1994 (PubMed)

  9. Cow (Bovine) Polyclonal GRIN2B Primary Antibody für IHC, WB - ABIN2776121 : Cais, Sedlacek, Horak, Dittert, Vyklicky: Temperature dependence of NR1/NR2B NMDA receptor channels. in Neuroscience 2008 (PubMed)

Weitere Antikörper gegen GRIN2B Interaktionspartner

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) Interaktionspartner

  1. Results indicate that the GRIN2B single nucleotide polymorphisms rs890 might be associated with schizophrenia in the Chinese Han population.

  2. These in vivo changes reflect changes in glutamate transporter (zeige SLC1A1 Antikörper) protein (zeige HNRNPU Antikörper) in Huntington's disease (HD), mice and human HD post-mortem (zeige NLRP1 Antikörper)tissue. Furthermore, NAC was able to rescue (zeige GRIN1 Antikörper)changes in key glutamate receptor proteins related to excitotoxicity in HD, including NMDAR2B.

  3. Genetic association of CYP2B6 (zeige CYP2B6 Antikörper)*6 and GRIN2B (rs1019385 and rs1806191) single-nucleotide polymorphisms and ketamine-induced EP occurrence.

  4. most rare variants in GluN2A (zeige GRIN2A Antikörper) were associated with epilepsy, whereas GluN2B variants were associated with intellectual disability with or without seizures

  5. In this review, mutations in GRIN2B were described as distributed throughout the entire gene in patients with neuropsychiatric and developmental disorders.

  6. Genetic variants were found in GluN2B from patients with neurological or psychiatric disorders resulting in reduced surface expression of GluN2B.

  7. Results found that GluN2B subunit-containing NMDARs were dominant in induced pluripotent stem cell-derived neurons and that tyrosine-protein kinase Fyn (zeige FYN Antikörper) potentiated the function of GluN2B subunit-containing NMDARs.

  8. Multiple genetic variants in GRIN2B are jointly associated with gene expression, prefrontal function and behaviour during working memory (WM). These results support the role of GRIN2B genetic variants in WM prefrontal activity in human adults.

  9. Findings do not support a role for GRIN2B variants in altering response to clozapine in our sample of European patients with schizophrenia deemed resistant or intolerant to treatment

  10. both Arf6 (zeige ARF6 Antikörper) activation through GluN2B-BRAG1 (zeige IQSEC2 Antikörper) during early development and the transition from BRAG1 (zeige IQSEC2 Antikörper)- to BRAG2 (zeige IQSEC1 Antikörper)-dependent Arf6 (zeige ARF6 Antikörper) signaling induced by the GluN2 subunit switch are critical for the development of mature glutamatergic synapses.

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) Interaktionspartner

  1. HumanTau(AT) causes excitotoxicity mediated by NR2B-containing NMDA receptors due to enhanced extracellular glutamate (zeige GRIN1 Antikörper).

  2. The NR2B-CREB (zeige CREB1 Antikörper)-miR212/132-CRTC1 (zeige CRTC1 Antikörper)-CREB (zeige CREB1 Antikörper) signal network plays an important role in the regulation of pain.

  3. This study demonstrated that Increasing the GluN2A (zeige GRIN2A Antikörper)/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

  4. These in vivo changes reflect changes in glutamate transporter (zeige SLC1A1 Antikörper) protein (zeige LAPTM4A Antikörper) in HD mice and human HD post-mortem tissue. Furthermore, NAC (zeige NLRP1 Antikörper) was able to rescue changes in key glutamate (zeige GRIN1 Antikörper) receptor proteins related to excitotoxicity in HD, including NMDAR2B.

  5. Data show that hydroxyproline HyP (zeige PHEX Antikörper)(10) plays a critical role in maintaining the structural integrity of conantokins conRl-B, which can be correlated with its glutamate (zeige GRIN1 Antikörper) receptor, ionotropic, N-methyl D-aspartate 2B (GluN2B) subunit-selective inhibition.

  6. These results highlight the requirement for stringent pharmacogenetic approaches to separate specific on-target effects from nonspecific off-target effects. Importantly, they also demonstrate that the CaMKII (zeige CAMK2G Antikörper)/GluN2B interaction is required not only for normal long-term potentiation induction but also for the maintenance of synaptic strength.

  7. GluN2B-dependent calcium signaling and excitatory postsynaptic current, long-term depression, and spatial reversal learning are enhanced in the hippocampus of AC6 (zeige ADCY6 Antikörper)(-/-) mice without altering the gross anatomy of the brain

  8. Unpredictable chronic mild stress mice exhibited elevated nucleus accumbens (NAC (zeige NLRP1 Antikörper)) shell levels of Glun2B. GluN2b levels were also lower within the NAC (zeige NLRP1 Antikörper) core.

  9. These data suggest that chronic early postnatal SSS influences spatial learning and memory ability, levels of hippocampal NR2B, and NR2A (zeige GRIN2A Antikörper)/NR2B ratios in adult males.

  10. Results identify crucial determinants in the C-terminal domain of GluN2B subunits in promoting neuronal death in ischemic conditions.

GRIN2B Antigen-Profil

Beschreibung des Gens

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Alternative names and synonyms associated with GRIN2B

  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B) Antikörper
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (Grin2b) Antikörper
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (grin2b) Antikörper
  • glutamate receptor, ionotropic, NMDA2B (epsilon 2) (Grin2b) Antikörper
  • AW490526 Antikörper
  • GluN2B Antikörper
  • hNR3 Antikörper
  • MRD6 Antikörper
  • Nmdar2b Antikörper
  • nr2b Antikörper

Bezeichner auf Proteinebene für GRIN2B

NMDA type glutamate receptor , N-methyl D-aspartate receptor subtype 2B , N-methyl-D-aspartate receptor subunit 2B , NMDAR2B , NR2B , glutamate [NMDA] receptor subunit epsilon-2 , glutamate receptor ionotropic, NMDA 2B , N-methyl-D-aspartate receptor subunit 3 , NR3 , glutamate receptor subunit epsilon-2 , glutamate receptor, ionotropic, NMDA2B , N-methyl-D-aspartate receptor subunit NR2B , GluRepsilon2 , N-methyl D-aspartate receptor 2B

GENE ID SPEZIES
751956 Taeniopygia guttata
494009 Canis lupus familiaris
2904 Homo sapiens
24410 Rattus norvegicus
100127347 Xenopus laevis
14812 Mus musculus
Ausgewählte Anbieter für anti-GRIN2B (GRIN2B) Antikörper
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