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Human Polyclonal ECE1 Primary Antibody für CyTOF, FACS - ABIN4900501
Cottrell, Padilla, Amadesi, Poole, Murphy, Hardt, Roosterman, Steinhoff, Bunnett: Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling. in The Journal of biological chemistry 2009
Show all 4 Pubmed References
ECE-1 and ECE-2 (zeige ECE2 Antikörper) levels were significantly reduced in post-mortem brains from dementia with Lewy body patients.
These results indicated that the ECE1 rs212528 and rs213045 polymorphisms had no major role to play in the genetic susceptibility to intracerebral haemorrhage.
results indicate that PKC (zeige PRRT2 Antikörper)-phosphorylated ECE-1 is a TIMAP (zeige PPP1R16B Antikörper)-PP1c substrate and this phosphatase complex has an important role in endothelin-1 (zeige EDN1 Antikörper) production of EC through the regulation of ECE-1 activity.
CK2 (zeige CSNK2A1 Antikörper)-increased ECE-1c protein stability is related to augmented migration and invasion of colon cancer cells, shedding light on a novel mechanism by which CK2 (zeige CSNK2A1 Antikörper) may promote malignant progression of this disease.
Thus, our findings suggest that ECE-1 may be a novel hypoxia-inducible factor-target gene.
Nitric oxide inhibits the production of soluble endothelin converting enzyme-1 by endothelial cells.
confirmed that endothelin-converting enzyme 1 (ECE1), EDN1 (zeige EDN1 Antikörper), and EDNRB (zeige EDNRB Antikörper) were involved in SP-induced pigmentation and found that EDN1 (zeige EDN1 Antikörper) secretion was affected by ECE1 and EDN1 (zeige EDN1 Antikörper) siRNAs, but not by EDNRB (zeige EDNRB Antikörper) siRNA
An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17 (zeige SOX17 Antikörper), FoxC2 (zeige FOXC2 Antikörper), and Etv2 (zeige ETV2 Antikörper)
Although the presence of a soluble form of ECE-1 has been demonstrated in vitro, it is yet to be shown in any human biological fluid. This study, used a combination of mass spectrometry, Western blotting & quenched fluorescent substrate based enzyme assays & showed presence of catalytically active, soluble form of ECE-1 in CSF (zeige CSF2 Antikörper) of subarachnoid hemorrhage subjects.
Data indicate endothelin-converting enzyme-1 (ECE-1) as a target for alternative polyadenylation (APA (zeige ENPEP Antikörper)), a regulatory mechanism aberrantly activated in cancer cells, and the mechanisms leading to ECE-1 overexpression in malignant cells.
The cardiac expression of prepro-endothelin-1 (zeige EDN1 Antikörper) mRNA, endothelin-converting enzyme-1 (zeige ECEL1 Antikörper) mRNA, and protein and endothelin receptors A and B mRNA was increased in 18-week-old obese C57BL/6 mice compared to animals with normal weight
identify the neural peptidase ECE-1 as a negative regulator of itch on sensory nerves by directly regulating ET-1 (zeige EDN1 Antikörper)-induced pruritus
differences in hemodynamic adn (zeige CFD Antikörper) ece1 expression between HcB-8 and HcB-23 arteries
Endothelin-converting enzyme-1 (zeige ECEL1 Antikörper) gene ablation attenuates pulmonary fibrosis via CGRP (zeige CALCA Antikörper)-cAMP/EPAC1 (zeige RAPGEF3 Antikörper) pathway.
involved in the physiological degradation of atrial natriuretic peptide (zeige NPPA Antikörper)
Ece1 is necessary for regression of the cranial arch arteries and growth of the most caudal arch arteries.
Our results provide evidence of structural conservation of mammalian genes encoding ECE-1 and will facilitate a more refined analysis of ECE-1 mRNA expression in the mouse model organism.
increased neuronal PKCepsilon (zeige PRKCE Antikörper) activity can promote Abeta (zeige APP Antikörper) clearance and reduce AD neuropathology through increased endothelin-converting enzyme activity
beta-amyloid levels in the brain are regulated by neprilysin (zeige MME Antikörper) and endothelin-converting enzyme but not angiotensin-converting enzyme (zeige ACE Antikörper)
reduced levels of endothelin converting enzyme-1 (zeige ECEL1 Antikörper) mRNA in the male mouse bowel at the time that enteric nervous system precursors migrate into the colon
The ECE1 transcript is constitutively expressed in the 10 tissues tested in Tibetan pig: the liver, subcutaneous fat, kidney, muscle, stomach, heart, brain, spleen, pancreas, and lung.
study suggests a possible role for endothelin-1 (zeige EDN1 Antikörper)(resulting from the actions of endothelin-converting enzyme-1) acting via endothelin receptor A (zeige EDNRA Antikörper) in the control of luteolytic sensitivity in the pig
Differential cell-specific and spatiotemporal expression of the EDN1 (zeige EDN1 Antikörper) system and NOS (zeige NOS Antikörper) in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.
Regulated during different stages of cycle. Hormonal regulation and intracellular localization of bovine ECE-1 isoforms may provide new insights into endothelin 1 (zeige EDN1 Antikörper) biosynthesis and mode of action in different cellular microenvironments within ovary.
It is suggested that endothelial cells sense shear stress as oxidative stress and transduce signal for the regulation of the gene expression of ECE.
presence of Endothelin-converting enzyme-1 isoforms in different endothelial cell compartments than full-length forms of the enzyme may suggest a distinct physiological role for these proteins
The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
, endothelin-converting enzyme 1
, endothelin-converting enzyme-1a
, endothelin-converting enzyme-1b
, endothelin-converting enzyme-1d
, Endothelin-converting enzyme 1
, endothelin converting enzyme-1